Characterization of Entamoeba histolytica adenosine 5'-phosphosulfate (APS) kinase; validation as a target and provision of leads for the development of new drugs against amoebiasis.

Characterization of Entamoeba histolytica adenosine 5'-phosphosulfate (APS) kinase; validation as a target and provision of leads for the development of new drugs against amoebiasis.

<h4>Background</h4>Amoebiasis, caused by Entamoeba histolytica infection, is a global public health problem. However, available drugs to treat amoebiasis are currently limited, and no effective vaccine exists. Therefore, development of new preventive measures against amoebiasis is urgent...

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Bibliographic Details
Main Authors: Fumika Mi-Ichi, Takeshi Ishikawa, Vo Kha Tam, Sharmina Deloer, Shinjiro Hamano, Tsuyoshi Hamada, Hiroki Yoshida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007633

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