Technological Advances: <i>CEBPA</i> and <i>FLT3</i> Internal Tandem Duplication Mutations Can be Reliably Detected by Next Generation Sequencing

Technological Advances: <i>CEBPA</i> and <i>FLT3</i> Internal Tandem Duplication Mutations Can be Reliably Detected by Next Generation Sequencing

Background: The detection of <i>CEBPA</i> and <i>FLT3</i> mutations by next generation sequencing (NGS) is challenging due to high GC content and Internal Tandem Duplications (ITDs). Recent advances have been made to surmount these challenges. In this study, we compare three...

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Bibliographic Details
Main Authors: Ratilal Akabari, Dahui Qin, Mohammad Hussaini
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Genes
Subjects:
<i>CEBPA</i>
<i>FLT3</i>
AML
next generation sequencing (NGS)
Internal Tandem Duplication (ITD)
Online Access:https://www.mdpi.com/2073-4425/13/4/630

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