Preventing invasive meningococcal disease in early infancy
This review considers the pathogenesis, diagnosis, and epidemiology of invasive meningococcal disease in infants, to examine and critique meningococcal disease prevention in this population through vaccination. High rates of meningococcal disease and poor outcomes, particularly for very young infant...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-11-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2021.1979846 |
| _version_ | 1797673329752014848 |
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| author | Jessica Presa Lidia Serra Catherine Weil-Olivier Laura York |
| author_facet | Jessica Presa Lidia Serra Catherine Weil-Olivier Laura York |
| author_sort | Jessica Presa |
| collection | DOAJ |
| description | This review considers the pathogenesis, diagnosis, and epidemiology of invasive meningococcal disease in infants, to examine and critique meningococcal disease prevention in this population through vaccination. High rates of meningococcal disease and poor outcomes, particularly for very young infants, highlight the importance of meningococcal vaccination in early infancy. Although effective and safe meningococcal vaccines are available for use from 6 weeks of age, they are not recommended globally. Emerging real-world data from the increased incorporation of these vaccines within immunization programs inform recommendations regarding effectiveness, appropriate vaccination schedule, possible long-term safety effects, and persistence of antibody responses. Importantly, to protect infants from IMD, national vaccination recommendations should be consistent with available data regarding vaccine safety, effectiveness, and disease risk. |
| first_indexed | 2024-03-11T21:43:00Z |
| format | Article |
| id | doaj.art-b94171185b474eb4aa295be0044ba118 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T21:43:00Z |
| publishDate | 2022-11-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-b94171185b474eb4aa295be0044ba1182023-09-26T12:43:41ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2022-11-0118510.1080/21645515.2021.19798461979846Preventing invasive meningococcal disease in early infancyJessica Presa0Lidia Serra1Catherine Weil-Olivier2Laura York3Pfizer IncPfizer IncUniversity Paris 7York Biologics Consulting LLCThis review considers the pathogenesis, diagnosis, and epidemiology of invasive meningococcal disease in infants, to examine and critique meningococcal disease prevention in this population through vaccination. High rates of meningococcal disease and poor outcomes, particularly for very young infants, highlight the importance of meningococcal vaccination in early infancy. Although effective and safe meningococcal vaccines are available for use from 6 weeks of age, they are not recommended globally. Emerging real-world data from the increased incorporation of these vaccines within immunization programs inform recommendations regarding effectiveness, appropriate vaccination schedule, possible long-term safety effects, and persistence of antibody responses. Importantly, to protect infants from IMD, national vaccination recommendations should be consistent with available data regarding vaccine safety, effectiveness, and disease risk.http://dx.doi.org/10.1080/21645515.2021.1979846infantmaternal vaccinationmeningococcalpassive immunityvaccination |
| spellingShingle | Jessica Presa Lidia Serra Catherine Weil-Olivier Laura York Preventing invasive meningococcal disease in early infancy Human Vaccines & Immunotherapeutics infant maternal vaccination meningococcal passive immunity vaccination |
| title | Preventing invasive meningococcal disease in early infancy |
| title_full | Preventing invasive meningococcal disease in early infancy |
| title_fullStr | Preventing invasive meningococcal disease in early infancy |
| title_full_unstemmed | Preventing invasive meningococcal disease in early infancy |
| title_short | Preventing invasive meningococcal disease in early infancy |
| title_sort | preventing invasive meningococcal disease in early infancy |
| topic | infant maternal vaccination meningococcal passive immunity vaccination |
| url | http://dx.doi.org/10.1080/21645515.2021.1979846 |
| work_keys_str_mv | AT jessicapresa preventinginvasivemeningococcaldiseaseinearlyinfancy AT lidiaserra preventinginvasivemeningococcaldiseaseinearlyinfancy AT catherineweilolivier preventinginvasivemeningococcaldiseaseinearlyinfancy AT laurayork preventinginvasivemeningococcaldiseaseinearlyinfancy |