Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery
Purpose: To investigate the safety and efficacy of endovascular embolization of cerebral aneurysms at the P1–P3 segments of the posterior cerebral artery (PCA).Materials and Methods: Seventy-seven patients with 77 PCA aneurysms who were treated with endovascular embolization were enrolled, including...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2021-10-01
|
| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2021.700516/full |
| _version_ | 1818729502336876544 |
|---|---|
| author | Xin-Yu Li Cong-Hui Li Ji-Wei Wang Jian-Feng Liu Hui Li Bu-Lang Gao |
| author_facet | Xin-Yu Li Cong-Hui Li Ji-Wei Wang Jian-Feng Liu Hui Li Bu-Lang Gao |
| author_sort | Xin-Yu Li |
| collection | DOAJ |
| description | Purpose: To investigate the safety and efficacy of endovascular embolization of cerebral aneurysms at the P1–P3 segments of the posterior cerebral artery (PCA).Materials and Methods: Seventy-seven patients with 77 PCA aneurysms who were treated with endovascular embolization were enrolled, including 35 (45.5%) patients with ruptured aneurysms and 42 (54.5%) with unruptured ones. The pretreatment clinical data and aneurysm occlusion status after treatment and at follow-up were analyzed.Results: All patients were successfully treated endovascularly, including coiling alone in 10 (13.0%) patients, stent-assisted coiling in 18 (23.4%), parent artery occlusion in 25 (32.5%), and pipeline embolization device (PED) in 24 (31.2%). Complete occlusion was achieved in 48 (62.3%) aneurysms, residual neck in 4 (5.2%), and residual aneurysm in the other 25 (32.5%) at the end of embolization. Periprocedural complications occurred in eight patients, including acute thrombosis in seven (9.1%) and intraprocedural subarachnoid hemorrhage in one (1.3%), with the total complication rate of 10.4%. Follow-up was performed in 60 patients (77.9%) for 42 ± 11 months; the mRS score was 0–2 in 55 (91.7%) patients, three in four patients (6.7%), and six in one patient (1.7%). Fifty-three (88.3%) patients (53 aneurysms) had stable or complete occlusion, and seven (11.7%) patients had aneurysm recurrence or residual aneurysm. Among 19 patients treated with PED at follow-up, 15 aneurysms (78.9%) proceeded to complete occlusion while four (21.1%) aneurysms showed residual aneurysm.Conclusion: Endovascular embolization remains a good choice of treatment with high safety and efficacy for posterior cerebral artery aneurysms. |
| first_indexed | 2024-12-17T22:46:54Z |
| format | Article |
| id | doaj.art-b943e3a7165d418da086d1bfb548e48b |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-17T22:46:54Z |
| publishDate | 2021-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-b943e3a7165d418da086d1bfb548e48b2022-12-21T21:29:46ZengFrontiers Media S.A.Frontiers in Neurology1664-22952021-10-011210.3389/fneur.2021.700516700516Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral ArteryXin-Yu LiCong-Hui LiJi-Wei WangJian-Feng LiuHui LiBu-Lang GaoPurpose: To investigate the safety and efficacy of endovascular embolization of cerebral aneurysms at the P1–P3 segments of the posterior cerebral artery (PCA).Materials and Methods: Seventy-seven patients with 77 PCA aneurysms who were treated with endovascular embolization were enrolled, including 35 (45.5%) patients with ruptured aneurysms and 42 (54.5%) with unruptured ones. The pretreatment clinical data and aneurysm occlusion status after treatment and at follow-up were analyzed.Results: All patients were successfully treated endovascularly, including coiling alone in 10 (13.0%) patients, stent-assisted coiling in 18 (23.4%), parent artery occlusion in 25 (32.5%), and pipeline embolization device (PED) in 24 (31.2%). Complete occlusion was achieved in 48 (62.3%) aneurysms, residual neck in 4 (5.2%), and residual aneurysm in the other 25 (32.5%) at the end of embolization. Periprocedural complications occurred in eight patients, including acute thrombosis in seven (9.1%) and intraprocedural subarachnoid hemorrhage in one (1.3%), with the total complication rate of 10.4%. Follow-up was performed in 60 patients (77.9%) for 42 ± 11 months; the mRS score was 0–2 in 55 (91.7%) patients, three in four patients (6.7%), and six in one patient (1.7%). Fifty-three (88.3%) patients (53 aneurysms) had stable or complete occlusion, and seven (11.7%) patients had aneurysm recurrence or residual aneurysm. Among 19 patients treated with PED at follow-up, 15 aneurysms (78.9%) proceeded to complete occlusion while four (21.1%) aneurysms showed residual aneurysm.Conclusion: Endovascular embolization remains a good choice of treatment with high safety and efficacy for posterior cerebral artery aneurysms.https://www.frontiersin.org/articles/10.3389/fneur.2021.700516/fullposterior cerebral arteryaneurysmendovascular embolizationstent-assistedcoiling |
| spellingShingle | Xin-Yu Li Cong-Hui Li Ji-Wei Wang Jian-Feng Liu Hui Li Bu-Lang Gao Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery Frontiers in Neurology posterior cerebral artery aneurysm endovascular embolization stent-assisted coiling |
| title | Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery |
| title_full | Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery |
| title_fullStr | Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery |
| title_full_unstemmed | Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery |
| title_short | Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery |
| title_sort | endovascular management of cerebral aneurysms of the posterior cerebral artery |
| topic | posterior cerebral artery aneurysm endovascular embolization stent-assisted coiling |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2021.700516/full |
| work_keys_str_mv | AT xinyuli endovascularmanagementofcerebralaneurysmsoftheposteriorcerebralartery AT conghuili endovascularmanagementofcerebralaneurysmsoftheposteriorcerebralartery AT jiweiwang endovascularmanagementofcerebralaneurysmsoftheposteriorcerebralartery AT jianfengliu endovascularmanagementofcerebralaneurysmsoftheposteriorcerebralartery AT huili endovascularmanagementofcerebralaneurysmsoftheposteriorcerebralartery AT bulanggao endovascularmanagementofcerebralaneurysmsoftheposteriorcerebralartery |