Clinico-pathological profile of pancytopenia patients in a single health care centre of northern India
Background: Pancytopenia is a clinical outcome of various pathological conditions ranging from bone marrow suppression, bone marrow infiltration, infections, hypersplenism, haemolysis, and haematological malignancies. As such is the most common cause in drug induced (chemotherapy) bone marrow suppre...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2022;volume=11;issue=6;spage=2952;epage=2955;aulast=Bhushan |
| _version_ | 1811217593903611904 |
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| author | Divendu Bhushan Rahul Shukla Ranjini Roy Mukta Agarwal |
| author_facet | Divendu Bhushan Rahul Shukla Ranjini Roy Mukta Agarwal |
| author_sort | Divendu Bhushan |
| collection | DOAJ |
| description | Background: Pancytopenia is a clinical outcome of various pathological conditions ranging from bone marrow suppression, bone marrow infiltration, infections, hypersplenism, haemolysis, and haematological malignancies. As such is the most common cause in drug induced (chemotherapy) bone marrow suppression. As most of these patients first contact their primary care physicians, a quick workup will resolve many diagnosis and can give a hint towards a life threatening condition too. Material and Methods: We included all patients admitted with pancytopenia at our tertiary care centre except those who were drug induced. They were evaluated and given appropriate treatment. Results: We observed 73 patients in a year, after excluding drug-induced pancytopenia, and showed aplastic anaemia was the foremost cause (31.5%) followed by vitamin B12 deficiency (19.2%), infections (13.7%), hypersplenism and haematological malignancies. Conclusion: Majority of adult patients admitted with pancytopenia are diagnosed to have curable cause like vitamin deficiency and infections but significant number was also of aplastic anaemia, a condition that requires specialist care. |
| first_indexed | 2024-04-12T06:57:28Z |
| format | Article |
| id | doaj.art-b949a1eede304d1181e934613af0f6aa |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-04-12T06:57:28Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-b949a1eede304d1181e934613af0f6aa2022-12-22T03:43:06ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632022-01-011162952295510.4103/jfmpc.jfmpc_2322_21Clinico-pathological profile of pancytopenia patients in a single health care centre of northern IndiaDivendu BhushanRahul ShuklaRanjini RoyMukta AgarwalBackground: Pancytopenia is a clinical outcome of various pathological conditions ranging from bone marrow suppression, bone marrow infiltration, infections, hypersplenism, haemolysis, and haematological malignancies. As such is the most common cause in drug induced (chemotherapy) bone marrow suppression. As most of these patients first contact their primary care physicians, a quick workup will resolve many diagnosis and can give a hint towards a life threatening condition too. Material and Methods: We included all patients admitted with pancytopenia at our tertiary care centre except those who were drug induced. They were evaluated and given appropriate treatment. Results: We observed 73 patients in a year, after excluding drug-induced pancytopenia, and showed aplastic anaemia was the foremost cause (31.5%) followed by vitamin B12 deficiency (19.2%), infections (13.7%), hypersplenism and haematological malignancies. Conclusion: Majority of adult patients admitted with pancytopenia are diagnosed to have curable cause like vitamin deficiency and infections but significant number was also of aplastic anaemia, a condition that requires specialist care.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2022;volume=11;issue=6;spage=2952;epage=2955;aulast=Bhushanaplastic anaemiachronic liver diseasehaemolytic anaemiamegaloblastic anaemiapancytopenia |
| spellingShingle | Divendu Bhushan Rahul Shukla Ranjini Roy Mukta Agarwal Clinico-pathological profile of pancytopenia patients in a single health care centre of northern India Journal of Family Medicine and Primary Care aplastic anaemia chronic liver disease haemolytic anaemia megaloblastic anaemia pancytopenia |
| title | Clinico-pathological profile of pancytopenia patients in a single health care centre of northern India |
| title_full | Clinico-pathological profile of pancytopenia patients in a single health care centre of northern India |
| title_fullStr | Clinico-pathological profile of pancytopenia patients in a single health care centre of northern India |
| title_full_unstemmed | Clinico-pathological profile of pancytopenia patients in a single health care centre of northern India |
| title_short | Clinico-pathological profile of pancytopenia patients in a single health care centre of northern India |
| title_sort | clinico pathological profile of pancytopenia patients in a single health care centre of northern india |
| topic | aplastic anaemia chronic liver disease haemolytic anaemia megaloblastic anaemia pancytopenia |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2022;volume=11;issue=6;spage=2952;epage=2955;aulast=Bhushan |
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