FLAME: A computerized neuropsychological composite for trials in early dementia

FLAME: A computerized neuropsychological composite for trials in early dementia

Abstract Introduction Sensitive neuropsychological tests are needed to improve power for clinical trials in early Alzheimer's disease (AD). Methods To develop a neuropsychological composite (FLAME – Factors of Longitudinal Attention, Memory and Executive Function), we assessed, 10,714 participa...

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Bibliographic Details
Main Authors: Helen Brooker, Gareth Williams, Adam Hampshire, Anne Corbett, Dag Aarsland, Jeffrey Cummings, Jose Luis Molinuevo, Alireza Atri, Zahinoor Ismail, Byron Creese, Tormod Fladby, Charlotte Thim‐Hansen, Keith Wesnes, Clive Ballard
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Alzheimer's
clinical trials
early dementia
MCI
PROTECT
sample size
Online Access:https://doi.org/10.1002/dad2.12098

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