Endothelial condition and hemostasis in acute leukemia
The review presents modern conceptions of disturbances in endothelial lining of the vessels and plasmic hemostasis in patients with acute leukemia; different mechanisms of coagulation disorders in acute leukemia: effects of leukemic cells containing procoagulants, fibrinolytic and antifibrinolytic s...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2011-07-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/30910 |
| _version_ | 1818884002820390912 |
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| author | Lyudmila Nikolaevna Tarasova Ol'ga Yur'evna Skol'skaya Sof'ya Gennad'evna Vladimirova L N Tarasova O Yu Skolskaya S G Vladimirova |
| author_facet | Lyudmila Nikolaevna Tarasova Ol'ga Yur'evna Skol'skaya Sof'ya Gennad'evna Vladimirova L N Tarasova O Yu Skolskaya S G Vladimirova |
| author_sort | Lyudmila Nikolaevna Tarasova |
| collection | DOAJ |
| description | The review presents modern conceptions of disturbances in endothelial lining of the vessels and plasmic hemostasis in patients with acute leukemia; different mechanisms of coagulation disorders in acute leukemia: effects of leukemic cells containing procoagulants, fibrinolytic and antifibrinolytic substances, of intensive chemotherapy and inflammation. All these impacts impair endothelial cells and trigger plasmic coagulation cascade; the initiator of coagulation is a tissue factor. Mechanisms of this process and statistics of thrombohemorrhagic complications in different variants of acute leukemia are outlined. |
| first_indexed | 2024-12-19T15:42:37Z |
| format | Article |
| id | doaj.art-b94ce2d35f224937953bf2b77830eb5a |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-19T15:42:37Z |
| publishDate | 2011-07-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-b94ce2d35f224937953bf2b77830eb5a2022-12-21T20:15:26Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422011-07-01837747827926Endothelial condition and hemostasis in acute leukemiaLyudmila Nikolaevna TarasovaOl'ga Yur'evna Skol'skayaSof'ya Gennad'evna VladimirovaL N Tarasova0O Yu Skolskaya1S G Vladimirova2Research Institute of Hematology and Blood Transfusion, KirovResearch Institute of Hematology and Blood Transfusion, KirovResearch Institute of Hematology and Blood Transfusion, KirovThe review presents modern conceptions of disturbances in endothelial lining of the vessels and plasmic hemostasis in patients with acute leukemia; different mechanisms of coagulation disorders in acute leukemia: effects of leukemic cells containing procoagulants, fibrinolytic and antifibrinolytic substances, of intensive chemotherapy and inflammation. All these impacts impair endothelial cells and trigger plasmic coagulation cascade; the initiator of coagulation is a tissue factor. Mechanisms of this process and statistics of thrombohemorrhagic complications in different variants of acute leukemia are outlined.https://ter-arkhiv.ru/0040-3660/article/view/30910acute leukemiaendotheliumhypercoagulationhemorrhagiathrombotic complications |
| spellingShingle | Lyudmila Nikolaevna Tarasova Ol'ga Yur'evna Skol'skaya Sof'ya Gennad'evna Vladimirova L N Tarasova O Yu Skolskaya S G Vladimirova Endothelial condition and hemostasis in acute leukemia Терапевтический архив acute leukemia endothelium hypercoagulation hemorrhagia thrombotic complications |
| title | Endothelial condition and hemostasis in acute leukemia |
| title_full | Endothelial condition and hemostasis in acute leukemia |
| title_fullStr | Endothelial condition and hemostasis in acute leukemia |
| title_full_unstemmed | Endothelial condition and hemostasis in acute leukemia |
| title_short | Endothelial condition and hemostasis in acute leukemia |
| title_sort | endothelial condition and hemostasis in acute leukemia |
| topic | acute leukemia endothelium hypercoagulation hemorrhagia thrombotic complications |
| url | https://ter-arkhiv.ru/0040-3660/article/view/30910 |
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