Mitochondrial Integrity and Function in the Progression of Early Pressure Overload–Induced Left Ventricular Remodeling

Mitochondrial Integrity and Function in the Progression of Early Pressure Overload–Induced Left Ventricular Remodeling

BackgroundFollowing pressure overload, compensatory concentric left ventricular remodeling (CR) variably transitions to eccentric remodeling (ER) and systolic dysfunction. Mechanisms responsible for this transition are incompletely understood. Here we leverage phenotypic variability in pressure over...

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Bibliographic Details
Main Authors: Antoine H. Chaanine, K Sreekumaran Nair, Robert H. Bergen, Katherine Klaus, Adam J. Guenzel, Roger J. Hajjar, Margaret M. Redfield
Format: Article
Language:English
Published: Wiley 2017-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
heart failure
hypertrophy
mitochondria
remodeling
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.005869

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