CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
CRISPR-based genetic elements can copy themselves across host genomes. Here the authors introduce CopyCatcher, a gene-drive related system for detecting and quantifying somatic gene conversion events.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-22927-1 |
| _version_ | 1818750497722466304 |
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| author | Zhiqian Li Nimi Marcel Sushil Devkota Ankush Auradkar Stephen M. Hedrick Valentino M. Gantz Ethan Bier |
| author_facet | Zhiqian Li Nimi Marcel Sushil Devkota Ankush Auradkar Stephen M. Hedrick Valentino M. Gantz Ethan Bier |
| author_sort | Zhiqian Li |
| collection | DOAJ |
| description | CRISPR-based genetic elements can copy themselves across host genomes. Here the authors introduce CopyCatcher, a gene-drive related system for detecting and quantifying somatic gene conversion events. |
| first_indexed | 2024-12-18T04:20:37Z |
| format | Article |
| id | doaj.art-b94ecd06f7bb42bcb6d8bcbcc6d0a9f1 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T04:20:37Z |
| publishDate | 2021-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-b94ecd06f7bb42bcb6d8bcbcc6d0a9f12022-12-21T21:21:15ZengNature PortfolioNature Communications2041-17232021-05-0112111210.1038/s41467-021-22927-1CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversionZhiqian Li0Nimi Marcel1Sushil Devkota2Ankush Auradkar3Stephen M. Hedrick4Valentino M. Gantz5Ethan Bier6Section of Cell and Developmental Biology, University of California San DiegoSection of Molecular Biology, University of California San DiegoSection of Cell and Developmental Biology, University of California San DiegoSection of Cell and Developmental Biology, University of California San DiegoSection of Molecular Biology, University of California San DiegoSection of Cell and Developmental Biology, University of California San DiegoSection of Cell and Developmental Biology, University of California San DiegoCRISPR-based genetic elements can copy themselves across host genomes. Here the authors introduce CopyCatcher, a gene-drive related system for detecting and quantifying somatic gene conversion events.https://doi.org/10.1038/s41467-021-22927-1 |
| spellingShingle | Zhiqian Li Nimi Marcel Sushil Devkota Ankush Auradkar Stephen M. Hedrick Valentino M. Gantz Ethan Bier CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion Nature Communications |
| title | CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion |
| title_full | CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion |
| title_fullStr | CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion |
| title_full_unstemmed | CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion |
| title_short | CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion |
| title_sort | copycatchers are versatile active genetic elements that detect and quantify inter homolog somatic gene conversion |
| url | https://doi.org/10.1038/s41467-021-22927-1 |
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