A comprehensive evaluation of sexual and reproductive outcomes following robot-assisted retroperitoneal lymph node dissection for nonseminomatous germ cell tumor
Sexual disorders following retroperitoneal pelvic lymph node dissection (RPLND) for testis tumor can affect the quality of life of patients. The aim of the current study was to investigate several different andrological outcomes, which may be influenced by robot-assisted (RA) RPLND. From January 201...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Asian Journal of Andrology |
| Subjects: | |
| Online Access: | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=6;spage=579;epage=583;aulast=Mistretta |
| _version_ | 1828286041119784960 |
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| author | Francesco A Mistretta Ottavio de Cobelli Paolo Verze Francesco Botticelli Letizia Jannello Stefano Luzzago Gabriele Cozzi Roberto Bianchi Ettore Di Trapani Matteo Ferro Giovanni Cordima Danilo Bottero Deliu Victor Matei Vincenzo Mirone Gennaro Musi |
| author_facet | Francesco A Mistretta Ottavio de Cobelli Paolo Verze Francesco Botticelli Letizia Jannello Stefano Luzzago Gabriele Cozzi Roberto Bianchi Ettore Di Trapani Matteo Ferro Giovanni Cordima Danilo Bottero Deliu Victor Matei Vincenzo Mirone Gennaro Musi |
| author_sort | Francesco A Mistretta |
| collection | DOAJ |
| description | Sexual disorders following retroperitoneal pelvic lymph node dissection (RPLND) for testis tumor can affect the quality of life of patients. The aim of the current study was to investigate several different andrological outcomes, which may be influenced by robot-assisted (RA) RPLND. From January 2012 to March 2020, 32 patients underwent RA-RPLND for stage I nonseminomatous testis cancer or postchemotherapy (PC) residual mass. Modified unilateral RPLND nerve-sparing template was always used. Major variables of interest were erectile dysfunction (ED), premature ejaculation (PE), dry ejaculation (DE), or orgasm alteration. Finally, fertility as well as the fecundation process (sexual intercourse or medically assisted procreation [MAP]) was investigated. Ten patients (31.3%) presented an andrological disorder of any type after RA-RPLND. Hypospermia was present in 4 (12.5%) patients, DE (International Index of Erectile Function-5 [IIEF-5] <25) in 3 (9.4%) patients, and ED in 3 (9.4%) patients. No PE or orgasmic alterations were described. Similar median age at surgery, body mass index (BMI), number of nodes removed, scholar status, and preoperative risk factor rates were identified between groups. Of all these 10 patients, 6 (60.0%) were treated at the beginning of our robotic experience (2012–2016). Of all 32 patients, 5 (15.6%) attempted to have a child after RA-RPLND. All of these 5 patients have successfully fathered children, but 2 (40.0%) required a MAP. In conclusion, a nonnegligible number of andrological complications occurred after RA-RPLND, mainly represented by ejaculation disorders, but ED occurrence and overall sexual satisfaction deficit should be definitely considered. No negative impact on fertility was described after RA-RPLND. |
| first_indexed | 2024-04-13T09:25:46Z |
| format | Article |
| id | doaj.art-b94f02dad30e40af99c50d0cc8c5c594 |
| institution | Directory Open Access Journal |
| issn | 1008-682X 1745-7262 |
| language | English |
| last_indexed | 2024-04-13T09:25:46Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Andrology |
| spelling | doaj.art-b94f02dad30e40af99c50d0cc8c5c5942022-12-22T02:52:28ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622022-01-0124657958310.4103/aja2021132A comprehensive evaluation of sexual and reproductive outcomes following robot-assisted retroperitoneal lymph node dissection for nonseminomatous germ cell tumorFrancesco A MistrettaOttavio de CobelliPaolo VerzeFrancesco BotticelliLetizia JannelloStefano LuzzagoGabriele CozziRoberto BianchiEttore Di TrapaniMatteo FerroGiovanni CordimaDanilo BotteroDeliu Victor MateiVincenzo MironeGennaro MusiSexual disorders following retroperitoneal pelvic lymph node dissection (RPLND) for testis tumor can affect the quality of life of patients. The aim of the current study was to investigate several different andrological outcomes, which may be influenced by robot-assisted (RA) RPLND. From January 2012 to March 2020, 32 patients underwent RA-RPLND for stage I nonseminomatous testis cancer or postchemotherapy (PC) residual mass. Modified unilateral RPLND nerve-sparing template was always used. Major variables of interest were erectile dysfunction (ED), premature ejaculation (PE), dry ejaculation (DE), or orgasm alteration. Finally, fertility as well as the fecundation process (sexual intercourse or medically assisted procreation [MAP]) was investigated. Ten patients (31.3%) presented an andrological disorder of any type after RA-RPLND. Hypospermia was present in 4 (12.5%) patients, DE (International Index of Erectile Function-5 [IIEF-5] <25) in 3 (9.4%) patients, and ED in 3 (9.4%) patients. No PE or orgasmic alterations were described. Similar median age at surgery, body mass index (BMI), number of nodes removed, scholar status, and preoperative risk factor rates were identified between groups. Of all these 10 patients, 6 (60.0%) were treated at the beginning of our robotic experience (2012–2016). Of all 32 patients, 5 (15.6%) attempted to have a child after RA-RPLND. All of these 5 patients have successfully fathered children, but 2 (40.0%) required a MAP. In conclusion, a nonnegligible number of andrological complications occurred after RA-RPLND, mainly represented by ejaculation disorders, but ED occurrence and overall sexual satisfaction deficit should be definitely considered. No negative impact on fertility was described after RA-RPLND.http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=6;spage=579;epage=583;aulast=Mistrettaandrology; lymph node excision; nonseminomatous germ cell tumor; robotics; testicular cancer |
| spellingShingle | Francesco A Mistretta Ottavio de Cobelli Paolo Verze Francesco Botticelli Letizia Jannello Stefano Luzzago Gabriele Cozzi Roberto Bianchi Ettore Di Trapani Matteo Ferro Giovanni Cordima Danilo Bottero Deliu Victor Matei Vincenzo Mirone Gennaro Musi A comprehensive evaluation of sexual and reproductive outcomes following robot-assisted retroperitoneal lymph node dissection for nonseminomatous germ cell tumor Asian Journal of Andrology andrology; lymph node excision; nonseminomatous germ cell tumor; robotics; testicular cancer |
| title | A comprehensive evaluation of sexual and reproductive outcomes following robot-assisted retroperitoneal lymph node dissection for nonseminomatous germ cell tumor |
| title_full | A comprehensive evaluation of sexual and reproductive outcomes following robot-assisted retroperitoneal lymph node dissection for nonseminomatous germ cell tumor |
| title_fullStr | A comprehensive evaluation of sexual and reproductive outcomes following robot-assisted retroperitoneal lymph node dissection for nonseminomatous germ cell tumor |
| title_full_unstemmed | A comprehensive evaluation of sexual and reproductive outcomes following robot-assisted retroperitoneal lymph node dissection for nonseminomatous germ cell tumor |
| title_short | A comprehensive evaluation of sexual and reproductive outcomes following robot-assisted retroperitoneal lymph node dissection for nonseminomatous germ cell tumor |
| title_sort | comprehensive evaluation of sexual and reproductive outcomes following robot assisted retroperitoneal lymph node dissection for nonseminomatous germ cell tumor |
| topic | andrology; lymph node excision; nonseminomatous germ cell tumor; robotics; testicular cancer |
| url | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=6;spage=579;epage=583;aulast=Mistretta |
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