Evaluation of Serum Homocysteine and Leptin Levels in Patients with Uveitis
Objectives: To evaluate the serum homocysteine (Hcy) and leptin levels in patients with uveitis. Materials and Methods: The 70 cases included in the study comprised 3 groups: patients with Behçet’s uveitis (BU), patients with non-Behçet’s uveitis (NBU) and healthy controls. Body mass index was cal...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2015-08-01
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| Series: | Türk Oftalmoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.oftalmoloji.org/article_9131/Evaluation-Of-Serum-Homocysteine-And-Leptin-Levels-In-Patients-With-Uveitis |
| Summary: | Objectives: To evaluate the serum homocysteine (Hcy) and leptin levels in patients with uveitis.
Materials and Methods: The 70 cases included in the study comprised 3 groups: patients with Behçet’s uveitis (BU), patients with
non-Behçet’s uveitis (NBU) and healthy controls. Body mass index was calculated for each subject. Serum Hcy and leptin levels were
measured. Furthermore, acute-phase reactants including erythrocyte sedimentation rate (ESR), C-reactive protein and neutrophil count
were measured.
Results: Serum Hcy levels were 15.04±4.59 µmol/L in the BU group, 15.4±6.87 µmol/L in the NBU group and 13.64±4.72 µmol/L
in the control group (p>0.05). The serum leptin levels of male patients in the BU group, NBU group and control group were 4.76±3.54
ng/ml, 6.33±3.74 ng/ml and 5.47±6.33 ng/ml, respectively (p>0.05). When we compared serum leptin levels in female patients and
controls, the mean serum leptin concentrations were significantly higher in female BU and NBU patients (24.83±17.62 ng/ml and
28.46±13.90 ng/ml, respectively) than in healthy control volunteers (9.62±6.36 ng/ml, p<0.05). In addition, the ESR value differences
between groups were statistically significant (p<0.05).
Conclusion: A larger case series is necessary to investigate serum Hcy and leptin concentrations in uveitis patients. (Turk J Ophthalmol
2015; 45: 146-151) |
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| ISSN: | 1300-0659 2147-2661 |