Adult Neurogenesis and the Promise of Adult Neural Stem Cells
The adult brain, even though largely postmitotic, is now known to have dividing cells that can make both glia and neurons. Of these, the precursor cells that have the potential to make new neurons in the adult brain have attracted great attention from researchers, anticipating their therapeutic pote...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2019-06-01
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| Series: | Journal of Experimental Neuroscience |
| Online Access: | https://doi.org/10.1177/1179069519856876 |
| _version_ | 1831724261216092160 |
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| author | Hiyaa S Ghosh |
| author_facet | Hiyaa S Ghosh |
| author_sort | Hiyaa S Ghosh |
| collection | DOAJ |
| description | The adult brain, even though largely postmitotic, is now known to have dividing cells that can make both glia and neurons. Of these, the precursor cells that have the potential to make new neurons in the adult brain have attracted great attention from researchers, anticipating their therapeutic potential for neurodegenerative conditions. In this review, I will focus on adult neurogenesis, from the perspective of the overall neurogenic potential in the adult brain, current understanding of the ‘adult neural stem cell’, and the importance of niche as a decisive factor for neurogenesis under homeostasis and pathologic conditions. |
| first_indexed | 2024-12-21T04:17:34Z |
| format | Article |
| id | doaj.art-b9559ec7027c4f3ea8a00de935a414b5 |
| institution | Directory Open Access Journal |
| issn | 1179-0695 |
| language | English |
| last_indexed | 2024-12-21T04:17:34Z |
| publishDate | 2019-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Experimental Neuroscience |
| spelling | doaj.art-b9559ec7027c4f3ea8a00de935a414b52022-12-21T19:16:16ZengSAGE PublishingJournal of Experimental Neuroscience1179-06952019-06-011310.1177/1179069519856876Adult Neurogenesis and the Promise of Adult Neural Stem CellsHiyaa S GhoshThe adult brain, even though largely postmitotic, is now known to have dividing cells that can make both glia and neurons. Of these, the precursor cells that have the potential to make new neurons in the adult brain have attracted great attention from researchers, anticipating their therapeutic potential for neurodegenerative conditions. In this review, I will focus on adult neurogenesis, from the perspective of the overall neurogenic potential in the adult brain, current understanding of the ‘adult neural stem cell’, and the importance of niche as a decisive factor for neurogenesis under homeostasis and pathologic conditions.https://doi.org/10.1177/1179069519856876 |
| spellingShingle | Hiyaa S Ghosh Adult Neurogenesis and the Promise of Adult Neural Stem Cells Journal of Experimental Neuroscience |
| title | Adult Neurogenesis and the Promise of Adult Neural Stem Cells |
| title_full | Adult Neurogenesis and the Promise of Adult Neural Stem Cells |
| title_fullStr | Adult Neurogenesis and the Promise of Adult Neural Stem Cells |
| title_full_unstemmed | Adult Neurogenesis and the Promise of Adult Neural Stem Cells |
| title_short | Adult Neurogenesis and the Promise of Adult Neural Stem Cells |
| title_sort | adult neurogenesis and the promise of adult neural stem cells |
| url | https://doi.org/10.1177/1179069519856876 |
| work_keys_str_mv | AT hiyaasghosh adultneurogenesisandthepromiseofadultneuralstemcells |