Marine Sponge Xestospongia sp.: A Promising Source for Tuberculosis Drug Development - Computational Insights into Mycobactin Biosynthesis Inhibition

Marine Sponge Xestospongia sp.: A Promising Source for Tuberculosis Drug Development - Computational Insights into Mycobactin Biosynthesis Inhibition

Mycobacterium tuberculosis (MTB) remains the leading cause of infection, with a significant fatality rate, owing primarily to drug resistance. MTB contains the enzyme salicylate synthase, which regulates mycobactin production to bind iron ions from the host cell, facilitating the bacteria to grow a...

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Bibliographic Details
Main Authors: Arfan Arfan, Aiyi Asnawi, La Ode Aman
Format: Article
Language:English
Published: Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya 2024-02-01
Series:Borneo Journal of Pharmacy
Subjects:
Docking
Molecular dynamics
Mycobacterium tuberculosis
Mycobactin
Salicylate synthase
Xestospongia sp.
Online Access:https://journal.umpr.ac.id/index.php/bjop/article/view/5513

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