The Prevalence of Mycobacterium Bovis in Patients with Pulmonary Tuberculosis in the Central Province, Iran
Background: Bovine tuberculosis, from the point of view of public health, is important in human societies. In this study, the prevalence of pulmonary tuberculosis caused by Mycobacterium bovis (M. bovis) in the central province, Iran, was reviewed. Methods: In this cross-sectional study, sputum cul...
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| Format: | Article |
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Isfahan University of Medical Sciences
2013-08-01
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| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/2539 |
| _version_ | 1797722155818942464 |
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| author | Aliasghar Farazi Masoomeh Sofian Mansoureh Jabbariasl Keyvan Tadayon Nader Mosavari Roohallah Keshavarz |
| author_facet | Aliasghar Farazi Masoomeh Sofian Mansoureh Jabbariasl Keyvan Tadayon Nader Mosavari Roohallah Keshavarz |
| author_sort | Aliasghar Farazi |
| collection | DOAJ |
| description | Background: Bovine tuberculosis, from the point of view of public health, is important in human societies. In this study, the prevalence of pulmonary tuberculosis caused by Mycobacterium bovis (M. bovis) in the central province, Iran, was reviewed.
Methods: In this cross-sectional study, sputum cultures were prepared from all smear-positive patients during 18 months. A culture medium containing pyruvate, as well as, chemical and molecular tests for the detection of M. bovis was used. Data analysis was performed using SPSS16 software.
Findings: During study, two strains of M. bovis were isolated. The molecular pattern of M. Bovis of the first patient by variable-number tandem repeat (VNTR) and spoligotyping methods was similar with most of M. bovis circulating in the population of cattle in Iran. But in the second case, despite being like a rare detected strain in the VNTR method, a different spoligotyping pattern was found. Eventually, it became clear that one of the isolates had not genotype similarity with the previously reported patterns.
Conclusion: The curriculum of bovine tuberculosis combatting consists of proper planningin control and eradication, mainly on the basis of repeated tuberculin testing, removing infected animals from the herd and slaughter them, pasteurization of milk, and human vaccination with Bacillus Calmette-Guérin (BCG) vaccine. |
| first_indexed | 2024-03-12T09:44:27Z |
| format | Article |
| id | doaj.art-b956ccc89aab4faa9b06d45857e2c203 |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T09:44:27Z |
| publishDate | 2013-08-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-b956ccc89aab4faa9b06d45857e2c2032023-09-02T13:01:44ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2013-08-01312397927991351The Prevalence of Mycobacterium Bovis in Patients with Pulmonary Tuberculosis in the Central Province, IranAliasghar Farazi0Masoomeh Sofian1Mansoureh Jabbariasl2Keyvan Tadayon3Nader Mosavari4Roohallah Keshavarz5Assistant Professor, Department of Infectious Diseases, School of Medicine, Arak University of Medical Sciences, Arak, IranAssociate Professor, Department of Infectious Diseases, School of Medicine, Arak University of Medical Sciences, Arak, IranResearcher, Department of Disease Control and Prevention, Health Center of Markazi Province, Arak, IranAssociate Professor, Razi Vaccine and Serum Research Institute, Karaj, IranAssociate Professor, Razi Vaccine and Serum Research Institute, Karaj, IranResearcher, Razi Vaccine and Serum Research Institute, Karaj, IranBackground: Bovine tuberculosis, from the point of view of public health, is important in human societies. In this study, the prevalence of pulmonary tuberculosis caused by Mycobacterium bovis (M. bovis) in the central province, Iran, was reviewed. Methods: In this cross-sectional study, sputum cultures were prepared from all smear-positive patients during 18 months. A culture medium containing pyruvate, as well as, chemical and molecular tests for the detection of M. bovis was used. Data analysis was performed using SPSS16 software. Findings: During study, two strains of M. bovis were isolated. The molecular pattern of M. Bovis of the first patient by variable-number tandem repeat (VNTR) and spoligotyping methods was similar with most of M. bovis circulating in the population of cattle in Iran. But in the second case, despite being like a rare detected strain in the VNTR method, a different spoligotyping pattern was found. Eventually, it became clear that one of the isolates had not genotype similarity with the previously reported patterns. Conclusion: The curriculum of bovine tuberculosis combatting consists of proper planningin control and eradication, mainly on the basis of repeated tuberculin testing, removing infected animals from the herd and slaughter them, pasteurization of milk, and human vaccination with Bacillus Calmette-Guérin (BCG) vaccine.http://jims.mui.ac.ir/index.php/jims/article/view/2539FrequencyMycobacterium bovisPulmonary tuberculosis |
| spellingShingle | Aliasghar Farazi Masoomeh Sofian Mansoureh Jabbariasl Keyvan Tadayon Nader Mosavari Roohallah Keshavarz The Prevalence of Mycobacterium Bovis in Patients with Pulmonary Tuberculosis in the Central Province, Iran مجله دانشکده پزشکی اصفهان Frequency Mycobacterium bovis Pulmonary tuberculosis |
| title | The Prevalence of Mycobacterium Bovis in Patients with Pulmonary Tuberculosis in the Central Province, Iran |
| title_full | The Prevalence of Mycobacterium Bovis in Patients with Pulmonary Tuberculosis in the Central Province, Iran |
| title_fullStr | The Prevalence of Mycobacterium Bovis in Patients with Pulmonary Tuberculosis in the Central Province, Iran |
| title_full_unstemmed | The Prevalence of Mycobacterium Bovis in Patients with Pulmonary Tuberculosis in the Central Province, Iran |
| title_short | The Prevalence of Mycobacterium Bovis in Patients with Pulmonary Tuberculosis in the Central Province, Iran |
| title_sort | prevalence of mycobacterium bovis in patients with pulmonary tuberculosis in the central province iran |
| topic | Frequency Mycobacterium bovis Pulmonary tuberculosis |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/2539 |
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