DNA demethylation upregulated Nrf2 expression in Alzheimer's disease cellular model

DNA demethylation upregulated Nrf2 expression in Alzheimer's disease cellular model

Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important transcription factor in the defense against oxidative stress. Cumulative evidence has shown that oxidative stress plays a key role in the pathogenesis of Alzheimer's disease (AD). Previous animal and clinical studies had observe...

Full description

Bibliographic Details
Main Authors:	Huimin eCao, Li eWang, Beibei eChen, Peng eZheng, Yi eHe, Yubin eDing, Yushuang eDeng, Xi eLu, Xiuming eGuo, Yuping eZhang, Yu eLi, Gang eYu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-01-01
Series:	Frontiers in Aging Neuroscience
Subjects:	Oxidative Stress Alzheimer's disease Nrf2 DNA demethylation NQO1 Cellular model
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00244/full

Similar Items

Genotypic variation in growth and physiological response to drought stress and re-watering reveals the critical role of recovery in drought adaptation in maize seedlings
by: Daoqian eChen, et al.
Published: (2016-01-01)

Histone acetylation modifiers in the pathogenesis of Alzheimer’s disease
by: Xi eLu, et al.
Published: (2015-06-01)

Graphene-based Materials for Photoanodes in Dye-sensitized Solar Cells
by: Xiaoru eGuo, et al.
Published: (2015-12-01)

Comparative analysis of the phytocyanin gene family in 10 plant species: a focus on Zea mays
by: Jun eCao, et al.
Published: (2015-07-01)

DNA methylation, a hand behind neurodegenerative disease
by: Haoyang eLu, et al.
Published: (2013-12-01)

Silicon enhanced salt tolerance by improving the root water uptake and decreasing the ion toxicity in cucumber
by: Shiwen eWang, et al.
Published: (2015-09-01)

Synaptic proteins and receptors defects in autism spectrum disorders
by: Jianling eChen, et al.
Published: (2014-09-01)

Lactobacillus protects the integrity of intestinal epithelial barrier damaged by pathogenic bacteria
by: Qinghua eYu, et al.
Published: (2015-03-01)

The sequence analysis of origin of replication in Saccharomyces cerevisiae genomes
by: Wen-Chao eLi, et al.
Published: (2014-11-01)

In vitro and in vivo analysis of antimicrobial agents alone and in combination against multi-drug resistant Acinetobacter baumannii
by: Songzhe eHE, et al.
Published: (2015-05-01)

The need to control for regression to the mean in social psychology studies
by: Rongjun eYu, et al.
Published: (2015-01-01)

Surgery-induced hippocampal angiotensin II elevation causes blood-brain barrier disruption via MMP/TIMP in aged rats
by: Zhengqian eLi, et al.
Published: (2016-04-01)

Regulation of Arsenite Oxidation by the Phosphate Two-Component System PhoBR in Halomonas sp. HAL1
by: Fang eChen, et al.
Published: (2015-09-01)

Overexpression of copper/zinc superoxide dismutase from mangrove Kandelia candel in tobacco enhances salinity tolerance by the reduction of reactive oxygen species in chloroplast
by: Xiaoshu eJing, et al.
Published: (2015-01-01)

The Effect of Word Frequency on Judgments of Learning: Contributions of Beliefs and Processing Fluency
by: Xiaoyu eJia, et al.
Published: (2016-01-01)

Genome-Wide Identification and Expression Analysis of the 14-3-3 Family Genes in Medicago truncatula
by: Cheng eQin, et al.
Published: (2016-03-01)

Skeletal cryptococcosis from 1977 to 2013
by: Hengxing eZhou, et al.
Published: (2015-01-01)

Four tomato FLOWERING LOCUS T-like proteins act antagonistically to regulate floral initiation
by: Kai eCao, et al.
Published: (2016-01-01)

From memory to prospection: The overlapping and the distinct components between remembering and imagining
by: Huimin eZheng, et al.
Published: (2014-08-01)

De novo sequencing of the leaf transcriptome reveals complex light-responsive regulatory networks in Camellia sinensis cv. Baijiguan
by: Quanjin eWu, et al.
Published: (2016-03-01)

Autoinducer-2 of Streptococcus mitis as a target molecule to inhibit pathogenic multi-species biofilm formation in vitro and in an endotracheal intubation rat model
by: Zhengli eWang, et al.
Published: (2016-02-01)

Integrative analysis of multiple diverse omics datasets by sparse group multitask regression
by: Dongdong eLin, et al.
Published: (2014-10-01)

Combining Self-Organizing Mapping and Supervised Affinity Propagation Clustering Approach to Investigate Functional Brain Networks Involved in Motor Imagery and Execution with fMRI Measurements
by: Jiang eZhang, et al.
Published: (2015-07-01)

The chemical and genetic characteristics of Szechuan pepper (Zanthoxylum bungeanum and Z. armatum) cultivars and their suitable habitat
by: Li eXiang, et al.
Published: (2016-04-01)

Dynamic Expression of Lgr6 in the Developing and Mature Mouse Cochlea
by: Yanping eZhang, et al.
Published: (2015-05-01)

Mapping the pathophysiology of schizophrenia: interactions between multiple cellular pathways
by: Chao eDeng, et al.
Published: (2013-11-01)

Effects of cognitive training on resting-state functional connectivity of default mode, salience and central executive networks
by: Weifang eCao, et al.
Published: (2016-04-01)

Functional preservation and reorganization of brain during motor imagery in patients with incomplete spinal cord injury: a pilot fMRI study
by: Xin eChen, et al.
Published: (2016-02-01)

Modulation of chloride channel functions by the plant lignan compounds kobusin and eudesmin
by: Yu eJiang, et al.
Published: (2015-11-01)

Highly efficient method for gene delivery in mouse dorsal root ganglia neurons
by: Lingli eYu, et al.
Published: (2015-02-01)

Mucosal SIV vaccines comprising inactivated virus particles and bacterial adjuvants induce CD8+T-regulatory cells that suppress SIV positive CD4+cell activation and prevent SIV infection in the macaque model.
by: Jean Marie eAndrieu, et al.
Published: (2014-06-01)

Blood disorders typically associated with renal transplantation
by: Yu eYang, et al.
Published: (2015-03-01)

Cortical thickness changes correlate with cognition changes after cognitive training: Evidence from a Chinese community study
by: Lijuan eJiang, et al.
Published: (2016-05-01)

The lateralization of intrinsic networks in the aging brain implicates the effects of cognitive training
by: Cheng eLuo, et al.
Published: (2016-03-01)

A High-Density Genetic Map of Cucumber Derived from Specific Length Amplified Fragment sequencing (SLAF-seq)
by: Xuewen eXu, et al.
Published: (2015-01-01)

Regulation of galactolipid biosynthesis by overexpression of the rice MGD gene contributes to enhanced aluminum tolerance in tobacco
by: Meijuan eZhang, et al.
Published: (2016-03-01)

Event-related brain potential correlates of prospective memory in symptomatically remitted male patients with schizophrenia
by: Guoliang eChen, et al.
Published: (2015-09-01)

Chemicals to enhance microalgal growth and accumulation of high-value bioproducts
by: Xinheng eYu, et al.
Published: (2015-02-01)

TRPA1 Mediates Amplified Sympathetic Responsiveness to Activation of Metabolically Sensitive Muscle Afferents in Rats with Femoral Artery Occlusion
by: Jihong eXing, et al.
Published: (2015-09-01)

Long-term boron-deficiency-responsive genes revealed by cDNA-AFLP differ between Citrus sinensis roots and leaves
by: Yi-Bin eLu, et al.
Published: (2015-07-01)