The Role of Macrophages in Oral Squamous Cell Carcinoma

The Role of Macrophages in Oral Squamous Cell Carcinoma

Oral cancer is a common malignancy worldwide, with high disease-related death rates. Oral squamous cell carcinoma (OSCC) accounts for more than 90% of oral tumors, with surgical management remaining the treatment of choice. However, advanced and metastatic OSCC is still incurable. Thus, emphasis has...

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Bibliographic Details
Main Authors: Eleni Marina Kalogirou, Konstantinos I. Tosios, Panagiotis F. Christopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
oral cancer
oral squamous cell carcinoma
tumor-associated macrophages (TAMs)
M1-M2 phenotype
classical activation
macrophage polarization
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.611115/full

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