Reduction of Pain and Bacterial Presence by using Double and Triple Antibiotic Pastes in Symptomatic Apical Periodontitis

OBJECTIVE: To compare the efficacy of calcium hydroxide, triple antibiotic paste and double antibiotic paste in reducing bacterial load and post treatment pain in symptomatic apical periodontitis. METHODOLOGY: In this comparative cross sectional study, 30 patients were divided into three groups. Af...

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Main Authors: Abdul Qadir Khan Dall, Farah Tasleem, Muhammad Farhan Khan, Kashif Ali Channar, Sarwat Batool, Muhammad Ahmed Bari
Format: Article
Language:English
Published: Liaquat University of Medical and Health Sciences 2019-06-01
Series:JLUMHS
Subjects:
Online Access:https://www.lumhs.edu.pk/jlumhs/Vol18No02/pdfs/11.pdf
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author Abdul Qadir Khan Dall
Farah Tasleem
Muhammad Farhan Khan
Kashif Ali Channar
Sarwat Batool
Muhammad Ahmed Bari
author_facet Abdul Qadir Khan Dall
Farah Tasleem
Muhammad Farhan Khan
Kashif Ali Channar
Sarwat Batool
Muhammad Ahmed Bari
author_sort Abdul Qadir Khan Dall
collection DOAJ
description OBJECTIVE: To compare the efficacy of calcium hydroxide, triple antibiotic paste and double antibiotic paste in reducing bacterial load and post treatment pain in symptomatic apical periodontitis. METHODOLOGY: In this comparative cross sectional study, 30 patients were divided into three groups. After sample collection Group A (control group) was medicated with calcium hydroxide (CH) paste, Group B with triple antibiotic paste (TAP) and Group C with double antibiotic paste (DAP). On day seven, pain status was checked by using visual analogue scale and canals were washed and another bacterial sample was taken and sent to laboratory to evaluate bacterial count. Evaluation of bacterial count and pain was done. Data analysis was performed in statistical packages for social sciences (SPSS) version 20.0. Mean & SD was calculated. Paired T-test was applied to compare qualitative data of control group with other two groups and P value (< 0.05) perceived as significant. RESULTS: All baseline samples were positive for bacteria with considerable pain. Following 07 days post-treatment VAS (visual analogue scale) showed mean value of 2.5±1.269 for CH, 1.7±0.823 for TAP and 2.0±1.054 for DAP. In post-treatment presence of Bacteria, mean was 1.1±0.316 for CH, 1.3±0.483 for TAP and 1.2±0.422 hence post treatment bacteria presence was lower in TAP and DAP and was higher in CH group. CONCLUSION: From the results it is concluded that DAP provided better antimicrobial effect with significant decrease in pain and bacterial count in comparison to control group and almost equal in efficacy to TAP.
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spelling doaj.art-b95d4513cfca4bafaab2f4001066daa92023-05-26T05:38:29ZengLiaquat University of Medical and Health SciencesJLUMHS1729-03412309-86272019-06-011802129135doi:10.22442/jlumhs.191820615Reduction of Pain and Bacterial Presence by using Double and Triple Antibiotic Pastes in Symptomatic Apical PeriodontitisAbdul Qadir Khan Dall 0Farah Tasleem1Muhammad Farhan Khan2Kashif Ali Channar3Sarwat Batool4Muhammad Ahmed Bari5Liaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Sindh-PakistanLiaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Sindh-PakistanBaqai Dental College, Baqai Medical UniversityLiaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Sindh-PakistanLiaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Sindh-PakistanServices Hospital, Karachi, Sindh-Pakistan.OBJECTIVE: To compare the efficacy of calcium hydroxide, triple antibiotic paste and double antibiotic paste in reducing bacterial load and post treatment pain in symptomatic apical periodontitis. METHODOLOGY: In this comparative cross sectional study, 30 patients were divided into three groups. After sample collection Group A (control group) was medicated with calcium hydroxide (CH) paste, Group B with triple antibiotic paste (TAP) and Group C with double antibiotic paste (DAP). On day seven, pain status was checked by using visual analogue scale and canals were washed and another bacterial sample was taken and sent to laboratory to evaluate bacterial count. Evaluation of bacterial count and pain was done. Data analysis was performed in statistical packages for social sciences (SPSS) version 20.0. Mean & SD was calculated. Paired T-test was applied to compare qualitative data of control group with other two groups and P value (< 0.05) perceived as significant. RESULTS: All baseline samples were positive for bacteria with considerable pain. Following 07 days post-treatment VAS (visual analogue scale) showed mean value of 2.5±1.269 for CH, 1.7±0.823 for TAP and 2.0±1.054 for DAP. In post-treatment presence of Bacteria, mean was 1.1±0.316 for CH, 1.3±0.483 for TAP and 1.2±0.422 hence post treatment bacteria presence was lower in TAP and DAP and was higher in CH group. CONCLUSION: From the results it is concluded that DAP provided better antimicrobial effect with significant decrease in pain and bacterial count in comparison to control group and almost equal in efficacy to TAP.https://www.lumhs.edu.pk/jlumhs/Vol18No02/pdfs/11.pdftriple antibiotic pastedouble antibiotic pastesymptomatic apical periodontitisintracanal medication.
spellingShingle Abdul Qadir Khan Dall
Farah Tasleem
Muhammad Farhan Khan
Kashif Ali Channar
Sarwat Batool
Muhammad Ahmed Bari
Reduction of Pain and Bacterial Presence by using Double and Triple Antibiotic Pastes in Symptomatic Apical Periodontitis
JLUMHS
triple antibiotic paste
double antibiotic paste
symptomatic apical periodontitis
intracanal medication.
title Reduction of Pain and Bacterial Presence by using Double and Triple Antibiotic Pastes in Symptomatic Apical Periodontitis
title_full Reduction of Pain and Bacterial Presence by using Double and Triple Antibiotic Pastes in Symptomatic Apical Periodontitis
title_fullStr Reduction of Pain and Bacterial Presence by using Double and Triple Antibiotic Pastes in Symptomatic Apical Periodontitis
title_full_unstemmed Reduction of Pain and Bacterial Presence by using Double and Triple Antibiotic Pastes in Symptomatic Apical Periodontitis
title_short Reduction of Pain and Bacterial Presence by using Double and Triple Antibiotic Pastes in Symptomatic Apical Periodontitis
title_sort reduction of pain and bacterial presence by using double and triple antibiotic pastes in symptomatic apical periodontitis
topic triple antibiotic paste
double antibiotic paste
symptomatic apical periodontitis
intracanal medication.
url https://www.lumhs.edu.pk/jlumhs/Vol18No02/pdfs/11.pdf
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