Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials

Liquid metals (LMs) have emerged as a new class of functional materials with attractive characteristics of low melting points and metal properties. Remarkable features, such as biocompatibility, injectability, plasticity, conductivity, and shape transformability, have rendered them as excellent cand...

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Main Authors: Xuyang Sun, Bo Yuan, Hongzhang Wang, Linlin Fan, Minghui Duan, Xuelin Wang, Rui Guo, Jing Liu
Format: Article
Language:English
Published: Wiley-VCH 2021-04-01
Series:Advanced NanoBiomed Research
Subjects:
Online Access:https://doi.org/10.1002/anbr.202000086
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author Xuyang Sun
Bo Yuan
Hongzhang Wang
Linlin Fan
Minghui Duan
Xuelin Wang
Rui Guo
Jing Liu
author_facet Xuyang Sun
Bo Yuan
Hongzhang Wang
Linlin Fan
Minghui Duan
Xuelin Wang
Rui Guo
Jing Liu
author_sort Xuyang Sun
collection DOAJ
description Liquid metals (LMs) have emerged as a new class of functional materials with attractive characteristics of low melting points and metal properties. Remarkable features, such as biocompatibility, injectability, plasticity, conductivity, and shape transformability, have rendered them as excellent candidates to tackle challenging biomedical issues, such as tumor clinics, tissue engineering, and even nerve connection. Scaling down the droplet size offers more opportunities in surface engineering and functionalization, thus providing broad biomedical scenarios expanding from drug delivery, enhanced bioheat transfer, tumor therapeutics, and bioelectronics to nanorobots. Despite in its infancy stage, a summary about the advancement of LM biomedical nanomaterials is urgently needed. This review aims to highlight the advantages of gallium‐based LM nanoparticles enabled nano‐biomedicine, to summarize the recent synthesis methods with diverse LM compositions, structures and surface modifications, and to introduce their typical state‐of‐the‐art biomedical applications. Challenges and opportunities are also discussed in the end.
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spelling doaj.art-b961b2f83de544d98521c726e2e55a002022-12-21T18:20:53ZengWiley-VCHAdvanced NanoBiomed Research2699-93072021-04-0114n/an/a10.1002/anbr.202000086Nano‐Biomedicine based on Liquid Metal Particles and Allied MaterialsXuyang Sun0Bo Yuan1Hongzhang Wang2Linlin Fan3Minghui Duan4Xuelin Wang5Rui Guo6Jing Liu7Beijing Key Lab of Cryo-Biomedical Engineering and Key Lab of Cryogenics Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 P.R. ChinaDepartment of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 P.R. ChinaDepartment of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 P.R. ChinaDepartment of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 P.R. ChinaDepartment of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 P.R. ChinaSchool of Medical Science and Engineering Beihang University Beijing 100191 P.R. ChinaDepartment of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 P.R. ChinaBeijing Key Lab of Cryo-Biomedical Engineering and Key Lab of Cryogenics Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 P.R. ChinaLiquid metals (LMs) have emerged as a new class of functional materials with attractive characteristics of low melting points and metal properties. Remarkable features, such as biocompatibility, injectability, plasticity, conductivity, and shape transformability, have rendered them as excellent candidates to tackle challenging biomedical issues, such as tumor clinics, tissue engineering, and even nerve connection. Scaling down the droplet size offers more opportunities in surface engineering and functionalization, thus providing broad biomedical scenarios expanding from drug delivery, enhanced bioheat transfer, tumor therapeutics, and bioelectronics to nanorobots. Despite in its infancy stage, a summary about the advancement of LM biomedical nanomaterials is urgently needed. This review aims to highlight the advantages of gallium‐based LM nanoparticles enabled nano‐biomedicine, to summarize the recent synthesis methods with diverse LM compositions, structures and surface modifications, and to introduce their typical state‐of‐the‐art biomedical applications. Challenges and opportunities are also discussed in the end.https://doi.org/10.1002/anbr.202000086biomaterialsliquid metalsnano-biomedicinenanoparticlessynthesis methods
spellingShingle Xuyang Sun
Bo Yuan
Hongzhang Wang
Linlin Fan
Minghui Duan
Xuelin Wang
Rui Guo
Jing Liu
Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials
Advanced NanoBiomed Research
biomaterials
liquid metals
nano-biomedicine
nanoparticles
synthesis methods
title Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials
title_full Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials
title_fullStr Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials
title_full_unstemmed Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials
title_short Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials
title_sort nano biomedicine based on liquid metal particles and allied materials
topic biomaterials
liquid metals
nano-biomedicine
nanoparticles
synthesis methods
url https://doi.org/10.1002/anbr.202000086
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AT xuelinwang nanobiomedicinebasedonliquidmetalparticlesandalliedmaterials
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