Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials
Liquid metals (LMs) have emerged as a new class of functional materials with attractive characteristics of low melting points and metal properties. Remarkable features, such as biocompatibility, injectability, plasticity, conductivity, and shape transformability, have rendered them as excellent cand...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley-VCH
2021-04-01
|
Series: | Advanced NanoBiomed Research |
Subjects: | |
Online Access: | https://doi.org/10.1002/anbr.202000086 |
_version_ | 1819156414920130560 |
---|---|
author | Xuyang Sun Bo Yuan Hongzhang Wang Linlin Fan Minghui Duan Xuelin Wang Rui Guo Jing Liu |
author_facet | Xuyang Sun Bo Yuan Hongzhang Wang Linlin Fan Minghui Duan Xuelin Wang Rui Guo Jing Liu |
author_sort | Xuyang Sun |
collection | DOAJ |
description | Liquid metals (LMs) have emerged as a new class of functional materials with attractive characteristics of low melting points and metal properties. Remarkable features, such as biocompatibility, injectability, plasticity, conductivity, and shape transformability, have rendered them as excellent candidates to tackle challenging biomedical issues, such as tumor clinics, tissue engineering, and even nerve connection. Scaling down the droplet size offers more opportunities in surface engineering and functionalization, thus providing broad biomedical scenarios expanding from drug delivery, enhanced bioheat transfer, tumor therapeutics, and bioelectronics to nanorobots. Despite in its infancy stage, a summary about the advancement of LM biomedical nanomaterials is urgently needed. This review aims to highlight the advantages of gallium‐based LM nanoparticles enabled nano‐biomedicine, to summarize the recent synthesis methods with diverse LM compositions, structures and surface modifications, and to introduce their typical state‐of‐the‐art biomedical applications. Challenges and opportunities are also discussed in the end. |
first_indexed | 2024-12-22T15:52:30Z |
format | Article |
id | doaj.art-b961b2f83de544d98521c726e2e55a00 |
institution | Directory Open Access Journal |
issn | 2699-9307 |
language | English |
last_indexed | 2024-12-22T15:52:30Z |
publishDate | 2021-04-01 |
publisher | Wiley-VCH |
record_format | Article |
series | Advanced NanoBiomed Research |
spelling | doaj.art-b961b2f83de544d98521c726e2e55a002022-12-21T18:20:53ZengWiley-VCHAdvanced NanoBiomed Research2699-93072021-04-0114n/an/a10.1002/anbr.202000086Nano‐Biomedicine based on Liquid Metal Particles and Allied MaterialsXuyang Sun0Bo Yuan1Hongzhang Wang2Linlin Fan3Minghui Duan4Xuelin Wang5Rui Guo6Jing Liu7Beijing Key Lab of Cryo-Biomedical Engineering and Key Lab of Cryogenics Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 P.R. ChinaDepartment of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 P.R. ChinaDepartment of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 P.R. ChinaDepartment of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 P.R. ChinaDepartment of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 P.R. ChinaSchool of Medical Science and Engineering Beihang University Beijing 100191 P.R. ChinaDepartment of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 P.R. ChinaBeijing Key Lab of Cryo-Biomedical Engineering and Key Lab of Cryogenics Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 P.R. ChinaLiquid metals (LMs) have emerged as a new class of functional materials with attractive characteristics of low melting points and metal properties. Remarkable features, such as biocompatibility, injectability, plasticity, conductivity, and shape transformability, have rendered them as excellent candidates to tackle challenging biomedical issues, such as tumor clinics, tissue engineering, and even nerve connection. Scaling down the droplet size offers more opportunities in surface engineering and functionalization, thus providing broad biomedical scenarios expanding from drug delivery, enhanced bioheat transfer, tumor therapeutics, and bioelectronics to nanorobots. Despite in its infancy stage, a summary about the advancement of LM biomedical nanomaterials is urgently needed. This review aims to highlight the advantages of gallium‐based LM nanoparticles enabled nano‐biomedicine, to summarize the recent synthesis methods with diverse LM compositions, structures and surface modifications, and to introduce their typical state‐of‐the‐art biomedical applications. Challenges and opportunities are also discussed in the end.https://doi.org/10.1002/anbr.202000086biomaterialsliquid metalsnano-biomedicinenanoparticlessynthesis methods |
spellingShingle | Xuyang Sun Bo Yuan Hongzhang Wang Linlin Fan Minghui Duan Xuelin Wang Rui Guo Jing Liu Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials Advanced NanoBiomed Research biomaterials liquid metals nano-biomedicine nanoparticles synthesis methods |
title | Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials |
title_full | Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials |
title_fullStr | Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials |
title_full_unstemmed | Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials |
title_short | Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials |
title_sort | nano biomedicine based on liquid metal particles and allied materials |
topic | biomaterials liquid metals nano-biomedicine nanoparticles synthesis methods |
url | https://doi.org/10.1002/anbr.202000086 |
work_keys_str_mv | AT xuyangsun nanobiomedicinebasedonliquidmetalparticlesandalliedmaterials AT boyuan nanobiomedicinebasedonliquidmetalparticlesandalliedmaterials AT hongzhangwang nanobiomedicinebasedonliquidmetalparticlesandalliedmaterials AT linlinfan nanobiomedicinebasedonliquidmetalparticlesandalliedmaterials AT minghuiduan nanobiomedicinebasedonliquidmetalparticlesandalliedmaterials AT xuelinwang nanobiomedicinebasedonliquidmetalparticlesandalliedmaterials AT ruiguo nanobiomedicinebasedonliquidmetalparticlesandalliedmaterials AT jingliu nanobiomedicinebasedonliquidmetalparticlesandalliedmaterials |