Microglia and macrophage metabolism: a regulator of cerebral gliomas

Microglia and macrophage metabolism: a regulator of cerebral gliomas

Abstract Reciprocal interactions between the tumor microenvironment (TME) and cancer cells play important roles in tumorigenesis and progression of glioma. Glioma-associated macrophages (GAMs), either of peripheral origin or representing brain-intrinsic microglia, are the majority population of infi...

Full description

Bibliographic Details
Main Authors:	Yue Deng, Qinyan Chen, Chao Wan, Yajie Sun, Fang Huang, Yan Hu, Kunyu Yang
Format:	Article
Language:	English
Published:	BMC 2024-04-01
Series:	Cell & Bioscience
Subjects:	Glioma Glioma-associated macrophages Metabolism Targeted therapy
Online Access:	https://doi.org/10.1186/s13578-024-01231-7

Similar Items

Epithelial-mesenchymal transition is the main way in which glioma-associated microglia/macrophages promote glioma progression
by: Xin He, et al.
Published: (2023-03-01)

Glioma-associated microglia/macrophages (GAMs) in glioblastoma: Immune function in the tumor microenvironment and implications for immunotherapy
by: Chao Lin, et al.
Published: (2023-03-01)

Origin, activation, and targeted therapy of glioma-associated macrophages
by: Can Xu, et al.
Published: (2022-10-01)

In Search for Reliable Markers of Glioma-Induced Polarization of Microglia
by: Kacper A. Walentynowicz, et al.
Published: (2018-06-01)

FTY720 Exerts Anti-Glioma Effects by Regulating the Glioma Microenvironment Through Increased CXCR4 Internalization by Glioma-Associated Microglia
by: Xu-Dong Guo, et al.
Published: (2020-03-01)

Recruitment mechanisms and therapeutic implications of tumor-associated macrophages in the glioma microenvironment
by: Xianzhe Zhou, et al.
Published: (2023-04-01)

Worldwide productivity and research trend of publications concerning glioma-associated macrophage/microglia: A bibliometric study
by: Yu-yang Liu, et al.
Published: (2022-12-01)

A Prediction Model for Deciphering Intratumoral Heterogeneity Derived from the Microglia/Macrophages of Glioma Using Non-Invasive Radiogenomics
by: Yunyang Zhu, et al.
Published: (2023-12-01)

Glioma conditioned medium promotes glycolysis and phenotypic transformation in macrophages
by: ZHANG Diya, LI Yunfan, GUO Hongjiang, QIU Jiaxing, WANG Yucheng, JU Rui, GUO Lei
Published: (2024-05-01)

Extracellular lipid loading augments hypoxic paracrine signaling and promotes glioma angiogenesis and macrophage infiltration
by: Svenja Offer, et al.
Published: (2019-06-01)

Tumor Associated Macrophages, as the Dominant Immune Cells, Are an Indispensable Target for Immunologically Cold Tumor—Glioma Therapy?
by: Ni Tong, et al.
Published: (2021-07-01)

The Importance of M1-and M2-Polarized Macrophages in Glioma and as Potential Treatment Targets
by: Jiangbin Ren, et al.
Published: (2023-08-01)

Tumor-associated microglia and macrophages in glioblastoma: From basic insights to therapeutic opportunities
by: Guoqing Wang, et al.
Published: (2022-07-01)

Microglia-Centered Combinatorial Strategies Against Glioblastoma
by: Tomás A. Martins, et al.
Published: (2020-09-01)

Acetylation Profiles in the Metabolic Process of Glioma-Associated Seizures
by: Ya-Wen Xu, et al.
Published: (2021-10-01)

Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma
by: Fatih Yalcin, et al.
Published: (2024-04-01)

Microglia and macrophages in glioblastoma: landscapes and treatment directions
by: Georgios Solomou, et al.
Published: (2024-12-01)

Glioma-Associated Stromal Cells Stimulate Glioma Malignancy by Regulating the Tumor Immune Microenvironment
by: Xiangming Cai, et al.
Published: (2021-04-01)

Hyaluronic acids mediate the infiltration, migration, and M2 polarization of macrophages: evaluating metabolic molecular phenotypes in gliomas
by: Hao Zhang, et al.
Published: (2022-12-01)

Cancer Metabolism: The Role of Immune Cells Epigenetic Alteration in Tumorigenesis, Progression, and Metastasis of Glioma
by: Kouminin Kanwore, et al.
Published: (2022-03-01)

Revealing the role of SPP1+ macrophages in glioma prognosis and therapeutic targeting by investigating tumor-associated macrophage landscape in grade 2 and 3 gliomas
by: Wenshu Tang, et al.
Published: (2024-03-01)

Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma
by: Verena Haage, et al.
Published: (2019-02-01)

Pathophysiological roles of integrins in gliomas from the perspective of glioma stem cells
by: Maoyu Wang, et al.
Published: (2022-09-01)

Microglia-Derived Microvesicles Affect Microglia Phenotype in Glioma
by: Alfonso Grimaldi, et al.
Published: (2019-02-01)

Single-Cell Omics in Dissecting Immune Microenvironment of Malignant Gliomas—Challenges and Perspectives
by: Bozena Kaminska, et al.
Published: (2021-08-01)

Hormones and immunity in cancer: are thyroid hormones endocrine players in the microglia/glioma cross-talk?
by: Cristiana ePerrotta, et al.
Published: (2015-06-01)

Diffuse midline glioma of the brainstem: genetic features, complications and treatment prospects
by: A. M. Kryanev, et al.
Published: (2024-06-01)

Editorial: Insights and implications of mechanisms shaping glioma immune landscape, immunotherapy resistance, and relevant translational research
by: Xiangqi Meng, et al.
Published: (2024-09-01)

Crosstalk between CD180-overexpression macrophages and glioma cells worsens patient survival through malignant phenotype promotion and immunosuppressive regulation
by: Wen Wang, et al.
Published: (2024-12-01)

Single-cell RNA sequencing identifies a subtype of FN1 + tumor-associated macrophages associated with glioma recurrence and as a biomarker for immunotherapy
by: Houshi Xu, et al.
Published: (2024-10-01)

Irradiation promotes an M2 macrophage phenotype in tumor hypoxia
by: Chi-Shiun eChiang, et al.
Published: (2012-08-01)

A Metabolic Plasticity-Based Signature for Molecular Classification and Prognosis of Lower-Grade Glioma
by: Ming-Chun Yang, et al.
Published: (2022-08-01)

Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma
by: Grant L. Lin, et al.
Published: (2018-06-01)

The role of tumor-associated macrophages in glioma cohort: through both traditional RNA sequencing and single cell RNA sequencing
by: Yunan Hou, et al.
Published: (2023-09-01)

CD44-Mediated Poor Prognosis in Glioma Is Associated With M2-Polarization of Tumor-Associated Macrophages and Immunosuppression
by: Yong Xiao, et al.
Published: (2022-02-01)

Mechanism of CXCL8 regulation of methionine metabolism to promote angiogenesis in gliomas
by: Jie Chang, et al.
Published: (2024-11-01)

V-ATPase in glioma stem cells: a novel metabolic vulnerability
by: Alessandra Maria Storaci, et al.
Published: (2025-01-01)

Intra‐Operative Definition of Glioma Infiltrative Margins by Visualizing Immunosuppressive Tumor‐Associated Macrophages
by: Chong Cao, et al.
Published: (2023-10-01)

High expression of stromal signatures correlated with macrophage infiltration, angiogenesis and poor prognosis in glioma microenvironment
by: Yixin Tian, et al.
Published: (2020-05-01)

Microglial SMAD4 regulated by microRNA-146a promotes migration of microglia which support tumor progression in a glioma environment
by: Dheen, S. Thameem, et al.
Published: (2018)