Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview
During the past few years, silver nanoparticles (AgNPs) became one of the most investigated and explored nanotechnology-derived nanostructures, given the fact that nanosilver-based materials proved to have interesting, challenging, and promising characteristics suitable for various biomedical applic...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-08-01
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| Series: | Nanomaterials |
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| Online Access: | http://www.mdpi.com/2079-4991/8/9/681 |
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| author | Alexandra-Cristina Burdușel Oana Gherasim Alexandru Mihai Grumezescu Laurențiu Mogoantă Anton Ficai Ecaterina Andronescu |
| author_facet | Alexandra-Cristina Burdușel Oana Gherasim Alexandru Mihai Grumezescu Laurențiu Mogoantă Anton Ficai Ecaterina Andronescu |
| author_sort | Alexandra-Cristina Burdușel |
| collection | DOAJ |
| description | During the past few years, silver nanoparticles (AgNPs) became one of the most investigated and explored nanotechnology-derived nanostructures, given the fact that nanosilver-based materials proved to have interesting, challenging, and promising characteristics suitable for various biomedical applications. Among modern biomedical potential of AgNPs, tremendous interest is oriented toward the therapeutically enhanced personalized healthcare practice. AgNPs proved to have genuine features and impressive potential for the development of novel antimicrobial agents, drug-delivery formulations, detection and diagnosis platforms, biomaterial and medical device coatings, tissue restoration and regeneration materials, complex healthcare condition strategies, and performance-enhanced therapeutic alternatives. Given the impressive biomedical-related potential applications of AgNPs, impressive efforts were undertaken on understanding the intricate mechanisms of their biological interactions and possible toxic effects. Within this review, we focused on the latest data regarding the biomedical use of AgNP-based nanostructures, including aspects related to their potential toxicity, unique physiochemical properties, and biofunctional behaviors, discussing herein the intrinsic anti-inflammatory, antibacterial, antiviral, and antifungal activities of silver-based nanostructures. |
| first_indexed | 2024-12-10T09:39:50Z |
| format | Article |
| id | doaj.art-b969603146b74512b855770ce607fd1f |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-12-10T09:39:50Z |
| publishDate | 2018-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-b969603146b74512b855770ce607fd1f2022-12-22T01:54:03ZengMDPI AGNanomaterials2079-49912018-08-018968110.3390/nano8090681nano8090681Biomedical Applications of Silver Nanoparticles: An Up-to-Date OverviewAlexandra-Cristina Burdușel0Oana Gherasim1Alexandru Mihai Grumezescu2Laurențiu Mogoantă3Anton Ficai4Ecaterina Andronescu5Faculty of Engineering in Foreign Languages, University Politehnica of Bucharest, 313 Splaiul Independenței, Bucharest 060042, RomaniaDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gheorghe Polizu Street, Bucharest 011061, RomaniaDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gheorghe Polizu Street, Bucharest 011061, RomaniaResearch Center for Microscopic Morphology and Immunology, University of Medicine and Pharmacy of Craiova, 2 Petru Rareș Street, Craiova 200349, RomaniaDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gheorghe Polizu Street, Bucharest 011061, RomaniaDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gheorghe Polizu Street, Bucharest 011061, RomaniaDuring the past few years, silver nanoparticles (AgNPs) became one of the most investigated and explored nanotechnology-derived nanostructures, given the fact that nanosilver-based materials proved to have interesting, challenging, and promising characteristics suitable for various biomedical applications. Among modern biomedical potential of AgNPs, tremendous interest is oriented toward the therapeutically enhanced personalized healthcare practice. AgNPs proved to have genuine features and impressive potential for the development of novel antimicrobial agents, drug-delivery formulations, detection and diagnosis platforms, biomaterial and medical device coatings, tissue restoration and regeneration materials, complex healthcare condition strategies, and performance-enhanced therapeutic alternatives. Given the impressive biomedical-related potential applications of AgNPs, impressive efforts were undertaken on understanding the intricate mechanisms of their biological interactions and possible toxic effects. Within this review, we focused on the latest data regarding the biomedical use of AgNP-based nanostructures, including aspects related to their potential toxicity, unique physiochemical properties, and biofunctional behaviors, discussing herein the intrinsic anti-inflammatory, antibacterial, antiviral, and antifungal activities of silver-based nanostructures.http://www.mdpi.com/2079-4991/8/9/681silver nanoparticlesbiomedical applicationsbiological interactionsbiofunctional performancesintrinsic anti-inflammatory activityantimicrobial efficiency |
| spellingShingle | Alexandra-Cristina Burdușel Oana Gherasim Alexandru Mihai Grumezescu Laurențiu Mogoantă Anton Ficai Ecaterina Andronescu Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview Nanomaterials silver nanoparticles biomedical applications biological interactions biofunctional performances intrinsic anti-inflammatory activity antimicrobial efficiency |
| title | Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview |
| title_full | Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview |
| title_fullStr | Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview |
| title_full_unstemmed | Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview |
| title_short | Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview |
| title_sort | biomedical applications of silver nanoparticles an up to date overview |
| topic | silver nanoparticles biomedical applications biological interactions biofunctional performances intrinsic anti-inflammatory activity antimicrobial efficiency |
| url | http://www.mdpi.com/2079-4991/8/9/681 |
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