Mutation Profile of Aggressive Pheochromocytoma and Paraganglioma with Comparison of TCGA Data

Mutation Profile of Aggressive Pheochromocytoma and Paraganglioma with Comparison of TCGA Data

In pheochromocytoma and paraganglioma (PPGL), germline or somatic mutations in one of the known susceptibility genes are identified in up to 60% patients. However, the peculiar genetic events that drive the aggressive behavior including metastasis in PPGL are poorly understood. We performed targeted...

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Bibliographic Details
Main Authors: Yun Mi Choi, Jinyeong Lim, Min Ji Jeon, Yu-Mi Lee, Tae-Yon Sung, Eun-Gyoung Hong, Ji-Young Lee, Se Jin Jang, Won Gu Kim, Dong Eun Song, Sung-Min Chun
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
aggressive pheochromocytoma
paraganglioma
DNA mutation analysis
high-throughput nucleotide sequencing
prognosis
Online Access:https://www.mdpi.com/2072-6694/13/10/2389

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