Natural and Synthetic Clay Minerals in the Pharmaceutical and Biomedical Fields
Clay minerals are historically among the most used materials with a wide variety of applications. In pharmaceutical and biomedical fields, their healing properties have always been known and used in pelotherapy and therefore attractive for their potential. In recent decades, the research has therefo...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Pharmaceutics |
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| Online Access: | https://www.mdpi.com/1999-4923/15/5/1368 |
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| author | Cristian Nomicisio Marco Ruggeri Eleonora Bianchi Barbara Vigani Caterina Valentino Carola Aguzzi Cesar Viseras Silvia Rossi Giuseppina Sandri |
| author_facet | Cristian Nomicisio Marco Ruggeri Eleonora Bianchi Barbara Vigani Caterina Valentino Carola Aguzzi Cesar Viseras Silvia Rossi Giuseppina Sandri |
| author_sort | Cristian Nomicisio |
| collection | DOAJ |
| description | Clay minerals are historically among the most used materials with a wide variety of applications. In pharmaceutical and biomedical fields, their healing properties have always been known and used in pelotherapy and therefore attractive for their potential. In recent decades, the research has therefore focused on the systematic investigation of these properties. This review aims to describe the most relevant and recent uses of clays in the pharmaceutical and biomedical field, especially for drug delivery and tissue engineering purposes. Clay minerals, which are biocompatible and non-toxic materials, can act as carriers for active ingredients while controlling their release and increasing their bioavailability. Moreover, the combination of clays and polymers is useful as it can improve the mechanical and thermal properties of polymers, as well as induce cell adhesion and proliferation. Different types of clays, both of natural (such as montmorillonite and halloysite) and synthetic origin (layered double hydroxides and zeolites), were considered in order to compare them and to assess their advantages and different uses. |
| first_indexed | 2024-03-11T03:24:41Z |
| format | Article |
| id | doaj.art-b96ff518c65c456ea8fb09bd2b340761 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-11T03:24:41Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-b96ff518c65c456ea8fb09bd2b3407612023-11-18T02:50:36ZengMDPI AGPharmaceutics1999-49232023-04-01155136810.3390/pharmaceutics15051368Natural and Synthetic Clay Minerals in the Pharmaceutical and Biomedical FieldsCristian Nomicisio0Marco Ruggeri1Eleonora Bianchi2Barbara Vigani3Caterina Valentino4Carola Aguzzi5Cesar Viseras6Silvia Rossi7Giuseppina Sandri8Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, ItalyDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, ItalyDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, ItalyDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, ItalyDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, ItalyDepartment of Pharmacy and Pharmaceutical Technology, University of Granada, Cartuja Campus, 18071 Granada, SpainDepartment of Pharmacy and Pharmaceutical Technology, University of Granada, Cartuja Campus, 18071 Granada, SpainDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, ItalyDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, ItalyClay minerals are historically among the most used materials with a wide variety of applications. In pharmaceutical and biomedical fields, their healing properties have always been known and used in pelotherapy and therefore attractive for their potential. In recent decades, the research has therefore focused on the systematic investigation of these properties. This review aims to describe the most relevant and recent uses of clays in the pharmaceutical and biomedical field, especially for drug delivery and tissue engineering purposes. Clay minerals, which are biocompatible and non-toxic materials, can act as carriers for active ingredients while controlling their release and increasing their bioavailability. Moreover, the combination of clays and polymers is useful as it can improve the mechanical and thermal properties of polymers, as well as induce cell adhesion and proliferation. Different types of clays, both of natural (such as montmorillonite and halloysite) and synthetic origin (layered double hydroxides and zeolites), were considered in order to compare them and to assess their advantages and different uses.https://www.mdpi.com/1999-4923/15/5/1368clay mineralsnanomaterialsdrug deliverytissue engineeringmontmorillonitehalloysite |
| spellingShingle | Cristian Nomicisio Marco Ruggeri Eleonora Bianchi Barbara Vigani Caterina Valentino Carola Aguzzi Cesar Viseras Silvia Rossi Giuseppina Sandri Natural and Synthetic Clay Minerals in the Pharmaceutical and Biomedical Fields Pharmaceutics clay minerals nanomaterials drug delivery tissue engineering montmorillonite halloysite |
| title | Natural and Synthetic Clay Minerals in the Pharmaceutical and Biomedical Fields |
| title_full | Natural and Synthetic Clay Minerals in the Pharmaceutical and Biomedical Fields |
| title_fullStr | Natural and Synthetic Clay Minerals in the Pharmaceutical and Biomedical Fields |
| title_full_unstemmed | Natural and Synthetic Clay Minerals in the Pharmaceutical and Biomedical Fields |
| title_short | Natural and Synthetic Clay Minerals in the Pharmaceutical and Biomedical Fields |
| title_sort | natural and synthetic clay minerals in the pharmaceutical and biomedical fields |
| topic | clay minerals nanomaterials drug delivery tissue engineering montmorillonite halloysite |
| url | https://www.mdpi.com/1999-4923/15/5/1368 |
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