A case of alemtuzumab-induced thyroid disease with a fluctuating course
Alemtuzumab (ALZ) is a humanized monoclonal antibody licensed for the treatment of relapsing–remitting multiple sclerosis (RRMS). One of its common side effects is autoimmune thyroid disease, most commonly Graves' disease (GD). Here, we present a case of a 39-year-old female that was on ALZ for...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Saudi Journal for Health Sciences |
| Subjects: | |
| Online Access: | http://www.saudijhealthsci.org/article.asp?issn=2278-0521;year=2023;volume=12;issue=2;spage=165;epage=166;aulast=Alghamdi |
| _version_ | 1797738479577202688 |
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| author | Sarah Ali Alghamdi Rha Ismail Shaza Samargandy |
| author_facet | Sarah Ali Alghamdi Rha Ismail Shaza Samargandy |
| author_sort | Sarah Ali Alghamdi |
| collection | DOAJ |
| description | Alemtuzumab (ALZ) is a humanized monoclonal antibody licensed for the treatment of relapsing–remitting multiple sclerosis (RRMS). One of its common side effects is autoimmune thyroid disease, most commonly Graves' disease (GD). Here, we present a case of a 39-year-old female that was on ALZ for the treatment of RRMS. After two cycles, she developed GD, which later converted to severe hypothyroidism. |
| first_indexed | 2024-03-12T13:43:26Z |
| format | Article |
| id | doaj.art-b970cbb9d06742b7b6ef2c51ffbd8785 |
| institution | Directory Open Access Journal |
| issn | 2278-0521 |
| language | English |
| last_indexed | 2024-03-12T13:43:26Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal for Health Sciences |
| spelling | doaj.art-b970cbb9d06742b7b6ef2c51ffbd87852023-08-23T09:47:29ZengWolters Kluwer Medknow PublicationsSaudi Journal for Health Sciences2278-05212023-01-0112216516610.4103/sjhs.sjhs_46_23A case of alemtuzumab-induced thyroid disease with a fluctuating courseSarah Ali AlghamdiRha IsmailShaza SamargandyAlemtuzumab (ALZ) is a humanized monoclonal antibody licensed for the treatment of relapsing–remitting multiple sclerosis (RRMS). One of its common side effects is autoimmune thyroid disease, most commonly Graves' disease (GD). Here, we present a case of a 39-year-old female that was on ALZ for the treatment of RRMS. After two cycles, she developed GD, which later converted to severe hypothyroidism.http://www.saudijhealthsci.org/article.asp?issn=2278-0521;year=2023;volume=12;issue=2;spage=165;epage=166;aulast=Alghamdialemtuzumabmultiple sclerosisthyroid disease |
| spellingShingle | Sarah Ali Alghamdi Rha Ismail Shaza Samargandy A case of alemtuzumab-induced thyroid disease with a fluctuating course Saudi Journal for Health Sciences alemtuzumab multiple sclerosis thyroid disease |
| title | A case of alemtuzumab-induced thyroid disease with a fluctuating course |
| title_full | A case of alemtuzumab-induced thyroid disease with a fluctuating course |
| title_fullStr | A case of alemtuzumab-induced thyroid disease with a fluctuating course |
| title_full_unstemmed | A case of alemtuzumab-induced thyroid disease with a fluctuating course |
| title_short | A case of alemtuzumab-induced thyroid disease with a fluctuating course |
| title_sort | case of alemtuzumab induced thyroid disease with a fluctuating course |
| topic | alemtuzumab multiple sclerosis thyroid disease |
| url | http://www.saudijhealthsci.org/article.asp?issn=2278-0521;year=2023;volume=12;issue=2;spage=165;epage=166;aulast=Alghamdi |
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