Production of a chimeric porcine reproductive and respiratory syndrome virus (PRRSV)-2 vaccine using a lab-scale packed-bed bioreactor CelCradle

Production of a chimeric porcine reproductive and respiratory syndrome virus (PRRSV)-2 vaccine using a lab-scale packed-bed bioreactor CelCradle

Abstract Background We developed a MARC-145 cell culture and porcine reproductive and respiratory syndrome (PRRS) vaccine production using a novel CelCradle bioreactor. CelCradle is a packed-bed bioreactor capable of both batch and perfusion culture, and the operating parameters are easy to optimize...

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Bibliographic Details
Main Authors: Hwi-Yeon Choi, Jong-Chul Choi, Yeong-Lim Kang, So-Hyeun Ahn, Sang-Won Lee, Seung-Yong Park, Chang-Seon Song, In-Soo Choi, Joong-Bok Lee
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Veterinary Research
Subjects:
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
Vaccine production
CelCradle
Packed Bed
Bioreactor
Vaccine efficacy
Online Access:https://doi.org/10.1186/s12917-023-03659-4

Internet

https://doi.org/10.1186/s12917-023-03659-4

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