Effects of early dexamethasone treatment on several markers of inflammation and fibrosis in an animal model of lung silicosis in rats – A pilot study

Effects of early dexamethasone treatment on several markers of inflammation and fibrosis in an animal model of lung silicosis in rats – A pilot study

Lung silicosis is primarily caused by inhalation of particles of silicon oxide (silica). Despite a huge progress in understanding the interactions among the pathomechanisms of lung silicosis in the last years, there is a lack of effective therapy. With respect to a wide therapeutic action of cortico...

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Bibliographic Details
Main Authors: Jana Adamcakova, Sona Balentova, Juliana Hanusrichterova, Romana Barosova, Pavol Mikolka, Kristian Prso, Juraj Mokry, Dagmar Kalenska, Lenka Kunertova, Daniela Mokra
Format: Article
Language:English
Published: Sciendo 2022-12-01
Series:Acta Medica Martiniana
Subjects:
lung silicosis
animal model
inflammation
oxidative stress
dexamethasone
Online Access:https://doi.org/10.2478/acm-2022-0012

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