Characterization and immobilization of engineered sialidases from <em>Trypanosoma rangeli</em> for transsialylation

Characterization and immobilization of engineered sialidases from <em>Trypanosoma rangeli</em> for transsialylation

A sialidase (EC 3.2.1.18; GH 33) from non-pathogenic <em>Trypanosoma rangeli</em> has been engineered with the aim of improving its transsialylation activity. Recently, two engineered variants containing 15 and 16 amino acid substitutions, respectively, were found to exhibit significantl...

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Bibliographic Details
Main Authors:	Birgitte Zeuner, Isabel González-Delgado, Jesper Holck, Gabriel Morales, María-José López-Muñoz, Yolanda Segura, Anne S. Meyer, Jørn Dalgaard Mikkelsen
Format:	Article
Language:	English
Published:	AIMS Press 2017-04-01
Series:	AIMS Molecular Science
Subjects:	Transsialylation transsialidase Trypanosoma rangeli enzyme immobilization casein glycomacropeptide (CGMP) GH33 human milk oligosaccharides (HMOs) galactooligosaccharides (GOS)
Online Access:	http://www.aimspress.com/Molecular/article/1376/fulltext.html

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