Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified

The aim of the article is to discuss the development of calcium channel blocker (CCB) influenced gingival enlargement. Data and Sources: MEDLINE/PubMed, Scopus, ScienceDirect, and Google Search databases. The article reviews contemporary and classic literature with a focus on pathophysiology, clinic...

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Main Authors: Pallavi Tonsekar, Vidya Tonsekar
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Oral
Subjects:
Online Access:https://www.mdpi.com/2673-6373/1/3/23
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author Pallavi Tonsekar
Vidya Tonsekar
author_facet Pallavi Tonsekar
Vidya Tonsekar
author_sort Pallavi Tonsekar
collection DOAJ
description The aim of the article is to discuss the development of calcium channel blocker (CCB) influenced gingival enlargement. Data and Sources: MEDLINE/PubMed, Scopus, ScienceDirect, and Google Search databases. The article reviews contemporary and classic literature with a focus on pathophysiology, clinical presentation, and risk factors associated with this condition. The application of various treatment options is also discussed. Study selection: Clinical studies, systematic reviews, in vitro studies, and case reports. Conclusion: Dental plaque, genetic predisposition, and type of drug used are critical in the development of drug-influenced gingival enlargement (DIGE). The surgical technique employed to treat the pathosis plays an important role in long term success of therapy. There has been an upward trend in occurrence of CCB-influenced gingival enlargement due to the unbridled use of CCBs. Due to the cosmetic and functional ramifications; the review underscores the importance of clinical research on prevention, treatment, and causes of recurrence of CCB-influenced gingival enlargement.
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spelling doaj.art-b9762072265b405f80870a90f8f306e22023-11-22T14:40:57ZengMDPI AGOral2673-63732021-08-011323624910.3390/oral1030023Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum DemystifiedPallavi Tonsekar0Vidya Tonsekar1Private Practice, Falls Church, VA 22042, USAPrivate Practice, Mumbai 400059, IndiaThe aim of the article is to discuss the development of calcium channel blocker (CCB) influenced gingival enlargement. Data and Sources: MEDLINE/PubMed, Scopus, ScienceDirect, and Google Search databases. The article reviews contemporary and classic literature with a focus on pathophysiology, clinical presentation, and risk factors associated with this condition. The application of various treatment options is also discussed. Study selection: Clinical studies, systematic reviews, in vitro studies, and case reports. Conclusion: Dental plaque, genetic predisposition, and type of drug used are critical in the development of drug-influenced gingival enlargement (DIGE). The surgical technique employed to treat the pathosis plays an important role in long term success of therapy. There has been an upward trend in occurrence of CCB-influenced gingival enlargement due to the unbridled use of CCBs. Due to the cosmetic and functional ramifications; the review underscores the importance of clinical research on prevention, treatment, and causes of recurrence of CCB-influenced gingival enlargement.https://www.mdpi.com/2673-6373/1/3/23drug-influenced gingival enlargementcalcium channel blockersadverse drug reactionsside effectnifedipineamlodipine
spellingShingle Pallavi Tonsekar
Vidya Tonsekar
Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified
Oral
drug-influenced gingival enlargement
calcium channel blockers
adverse drug reactions
side effect
nifedipine
amlodipine
title Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified
title_full Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified
title_fullStr Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified
title_full_unstemmed Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified
title_short Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified
title_sort calcium channel blocker influenced gingival enlargement a conundrum demystified
topic drug-influenced gingival enlargement
calcium channel blockers
adverse drug reactions
side effect
nifedipine
amlodipine
url https://www.mdpi.com/2673-6373/1/3/23
work_keys_str_mv AT pallavitonsekar calciumchannelblockerinfluencedgingivalenlargementaconundrumdemystified
AT vidyatonsekar calciumchannelblockerinfluencedgingivalenlargementaconundrumdemystified