B‑nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2022-01-01
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| Series: | ACS Omega |
| Online Access: | https://doi.org/10.1021/acsomega.1c04659 |
| _version_ | 1818954808750505984 |
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| author | Andreas Stein Persefoni Hilken née Thomopoulou Corazon Frias Sina M. Hopff Paloma Varela Nicola Wilke Arul Mariappan Jörg-Martin Neudörfl Alexey Yu Fedorov Jay Gopalakrishnan Benoît Gigant Aram Prokop Hans-Günther Schmalz |
| author_facet | Andreas Stein Persefoni Hilken née Thomopoulou Corazon Frias Sina M. Hopff Paloma Varela Nicola Wilke Arul Mariappan Jörg-Martin Neudörfl Alexey Yu Fedorov Jay Gopalakrishnan Benoît Gigant Aram Prokop Hans-Günther Schmalz |
| author_sort | Andreas Stein |
| collection | DOAJ |
| first_indexed | 2024-12-20T10:28:03Z |
| format | Article |
| id | doaj.art-b9771bb895fa4ea4b4685ea98a2825e6 |
| institution | Directory Open Access Journal |
| issn | 2470-1343 |
| language | English |
| last_indexed | 2024-12-20T10:28:03Z |
| publishDate | 2022-01-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | ACS Omega |
| spelling | doaj.art-b9771bb895fa4ea4b4685ea98a2825e62022-12-21T19:43:47ZengAmerican Chemical SocietyACS Omega2470-13432022-01-01732591260310.1021/acsomega.1c04659B‑nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent MannerAndreas Stein0Persefoni Hilken née Thomopoulou1Corazon Frias2Sina M. Hopff3Paloma Varela4Nicola Wilke5Arul Mariappan6Jörg-Martin Neudörfl7Alexey Yu Fedorov8Jay Gopalakrishnan9Benoît Gigant10Aram Prokop11Hans-Günther Schmalz12Department of Chemistry, University of Cologne, Cologne, GermanyDepartment of Chemistry, University of Cologne, Cologne, GermanyDepartment of Paediatric Oncology, Children’s Hospital Cologne, Cologne, GermanyDepartment of Paediatric Oncology, Children’s Hospital Cologne, Cologne, GermanyUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette cedex, FranceDepartment of Paediatric Oncology, Children’s Hospital Cologne, Cologne, GermanyLaboratory for Centrosome and Cytoskeleton Biology, Institute of Human Genetics, Heinrich-Heine-University, Düsseldorf, GermanyDepartment of Chemistry, University of Cologne, Cologne, GermanyDepartment of Organic Chemistry, N.I. Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russian FederationLaboratory for Centrosome and Cytoskeleton Biology, Institute of Human Genetics, Heinrich-Heine-University, Düsseldorf, GermanyUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette cedex, FranceDepartment of Paediatric Oncology, Children’s Hospital Cologne, Cologne, GermanyDepartment of Chemistry, University of Cologne, Cologne, Germanyhttps://doi.org/10.1021/acsomega.1c04659 |
| spellingShingle | Andreas Stein Persefoni Hilken née Thomopoulou Corazon Frias Sina M. Hopff Paloma Varela Nicola Wilke Arul Mariappan Jörg-Martin Neudörfl Alexey Yu Fedorov Jay Gopalakrishnan Benoît Gigant Aram Prokop Hans-Günther Schmalz B‑nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner ACS Omega |
| title | B‑nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner |
| title_full | B‑nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner |
| title_fullStr | B‑nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner |
| title_full_unstemmed | B‑nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner |
| title_short | B‑nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner |
| title_sort | b nor methylene colchicinoid pt 100 selectively induces apoptosis in multidrug resistant human cancer cells via an intrinsic pathway in a caspase independent manner |
| url | https://doi.org/10.1021/acsomega.1c04659 |
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