Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia
Abstract Background Wildlife may harbor infectious pathogens that are of zoonotic concern acting as a reservoir of diseases transmissible to humans and domestic animals. This is due to human-wildlife conflicts that have become more frequent and severe over recent decades, competition for the availab...
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| Format: | Article |
| Language: | English |
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BMC
2014-10-01
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| Series: | Parasites & Vectors |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13071-014-0490-x |
| _version_ | 1827933721050742784 |
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| author | Jesca Nakayima Kyoko Hayashida Ryo Nakao Akihiro Ishii Hirohito Ogawa Ichiro Nakamura Ladslav Moonga Bernard M Hang’ombe Aaron S Mweene Yuka Thomas Yasuko Orba Hirofumi Sawa Chihiro Sugimoto |
| author_facet | Jesca Nakayima Kyoko Hayashida Ryo Nakao Akihiro Ishii Hirohito Ogawa Ichiro Nakamura Ladslav Moonga Bernard M Hang’ombe Aaron S Mweene Yuka Thomas Yasuko Orba Hirofumi Sawa Chihiro Sugimoto |
| author_sort | Jesca Nakayima |
| collection | DOAJ |
| description | Abstract Background Wildlife may harbor infectious pathogens that are of zoonotic concern acting as a reservoir of diseases transmissible to humans and domestic animals. This is due to human-wildlife conflicts that have become more frequent and severe over recent decades, competition for the available natural habitats and resources leading to increased human encroachment on previously wild and uninhabited areas. Methods A total of 88 spleen DNA samples from baboons and vervet monkeys from Zambia were tested for zoonotic pathogens using genus or species-specific PCR. The amplified products were then subjected to sequencing analysis. Results We detected three different pathogenic agents, including Anaplasma phagocytophilum in 12 samples (13.6%), Rickettsia spp. in 35 samples (39.8%) and Babesia spp. in 2 samples (2.3%). Conclusion The continuously increasing contacts between humans and primate populations raise concerns about transmission of pathogens between these groups. Therefore, increased medical and public awareness and public health surveillance support will be required to detect and control infections caused by these agents at the interface between humans and wildlife. |
| first_indexed | 2024-03-13T07:28:44Z |
| format | Article |
| id | doaj.art-b979b4b8cb464b59b22dc184855b5b4a |
| institution | Directory Open Access Journal |
| issn | 1756-3305 |
| language | English |
| last_indexed | 2024-03-13T07:28:44Z |
| publishDate | 2014-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Parasites & Vectors |
| spelling | doaj.art-b979b4b8cb464b59b22dc184855b5b4a2023-06-04T11:15:46ZengBMCParasites & Vectors1756-33052014-10-01711710.1186/s13071-014-0490-xDetection and characterization of zoonotic pathogens of free-ranging non-human primates from ZambiaJesca Nakayima0Kyoko Hayashida1Ryo Nakao2Akihiro Ishii3Hirohito Ogawa4Ichiro Nakamura5Ladslav Moonga6Bernard M Hang’ombe7Aaron S Mweene8Yuka Thomas9Yasuko Orba10Hirofumi Sawa11Chihiro Sugimoto12Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido UniversityDivision of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido UniversityUnit of Risk Analysis and Management, Research Center for Zoonosis Control, Hokkaido UniversityHokudai Center for Zoonosis Control in Zambia, School of Veterinary Medicine, University of ZambiaHokudai Center for Zoonosis Control in Zambia, School of Veterinary Medicine, University of ZambiaDivision of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido UniversityDepartment of Paraclinical Studies, School of Veterinary Medicine, University of ZambiaDepartment of Paraclinical Studies, School of Veterinary Medicine, University of ZambiaDepartment of Disease Control, School of Veterinary Medicine, University of ZambiaHokudai Center for Zoonosis Control in Zambia, School of Veterinary Medicine, University of ZambiaDivision of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, N20, W10Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, N20, W10Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido UniversityAbstract Background Wildlife may harbor infectious pathogens that are of zoonotic concern acting as a reservoir of diseases transmissible to humans and domestic animals. This is due to human-wildlife conflicts that have become more frequent and severe over recent decades, competition for the available natural habitats and resources leading to increased human encroachment on previously wild and uninhabited areas. Methods A total of 88 spleen DNA samples from baboons and vervet monkeys from Zambia were tested for zoonotic pathogens using genus or species-specific PCR. The amplified products were then subjected to sequencing analysis. Results We detected three different pathogenic agents, including Anaplasma phagocytophilum in 12 samples (13.6%), Rickettsia spp. in 35 samples (39.8%) and Babesia spp. in 2 samples (2.3%). Conclusion The continuously increasing contacts between humans and primate populations raise concerns about transmission of pathogens between these groups. Therefore, increased medical and public awareness and public health surveillance support will be required to detect and control infections caused by these agents at the interface between humans and wildlife.https://doi.org/10.1186/s13071-014-0490-xNon-human primatesReservoirPathogensZoonosisZambia |
| spellingShingle | Jesca Nakayima Kyoko Hayashida Ryo Nakao Akihiro Ishii Hirohito Ogawa Ichiro Nakamura Ladslav Moonga Bernard M Hang’ombe Aaron S Mweene Yuka Thomas Yasuko Orba Hirofumi Sawa Chihiro Sugimoto Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia Parasites & Vectors Non-human primates Reservoir Pathogens Zoonosis Zambia |
| title | Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia |
| title_full | Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia |
| title_fullStr | Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia |
| title_full_unstemmed | Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia |
| title_short | Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia |
| title_sort | detection and characterization of zoonotic pathogens of free ranging non human primates from zambia |
| topic | Non-human primates Reservoir Pathogens Zoonosis Zambia |
| url | https://doi.org/10.1186/s13071-014-0490-x |
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