A Robust Prognostic Gene Signature Based on eRNAs-Driven Genes in Prostate Cancer

A Robust Prognostic Gene Signature Based on eRNAs-Driven Genes in Prostate Cancer

Prostate cancer (PCa) is the second most common malignancy in men, but its exact pathogenetic mechanisms remain unclear. This study explores the effect of enhancer RNAs (eRNAs) in PCa. Firstly, we screened eRNAs and eRNA -driven genes from The Cancer Genome Atlas (TCGA) database, which are related t...

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Bibliographic Details
Main Authors: Shuaishuai Fan, Zheng Wang, Li Zhao, ChenHui Zhao, DaJiang Yuan, Jingqi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
prostate cancer
enhancer RNA
prognostic gene signature
risk score model
drug sensitivity
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.676845/full

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