NT-proBNP—Possible Prognostic Marker in Pregnant Patients with Associated Cardiovascular Risk Factors and SARS-CoV-2 Infection
Background: N-terminal pro brain-type natriuretic peptide (NT-proBNP) is a practical biomarker in the clinical pathologies where the ventricle is under stress and particularly stretched in the general population. The study aims to compare the value of NT-proBNP and its importance in the prognosis an...
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MDPI AG
2023-09-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/19/3032 |
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| author | Carmen-Ioana Marta Anca Laura Maghiari Elena Bernad Lavinia Stelea Brenda Bernad Lioara Boscu Radu Neamtu Adrian Gluhovschi Mircea Diaconu Catalin Dumitru Bogdan Sorop Katalin Babes |
| author_facet | Carmen-Ioana Marta Anca Laura Maghiari Elena Bernad Lavinia Stelea Brenda Bernad Lioara Boscu Radu Neamtu Adrian Gluhovschi Mircea Diaconu Catalin Dumitru Bogdan Sorop Katalin Babes |
| author_sort | Carmen-Ioana Marta |
| collection | DOAJ |
| description | Background: N-terminal pro brain-type natriuretic peptide (NT-proBNP) is a practical biomarker in the clinical pathologies where the ventricle is under stress and particularly stretched in the general population. The study aims to compare the value of NT-proBNP and its importance in the prognosis and severity of the cases involving pregnant patients with SARS-CoV-2 infection and cardiovascular risk factors to those of low-risk pregnant patients, mainly by analysing their symptoms, administered medication, days of hospitalization and severity of the viral disease. Methods: The study included a total of eighty-three pregnant patients who underwent natural birth or caesarean section at out hospital. NT-proBNP levels were analyzed at hospital admission as a potential cardiovascular marker. A comparative analysis was performed between pregnant patients with cardiovascular risk factors and pregnant patients without cardiovascular risk factors regarding NT-proBNP values. Results: Pregnant patients with SARS-CoV-2 infection and cardiovascular risk factors had higher values of NT-proBNP in comparison to pregnant patients without cardiovascular risk factors. Conclusions: NT-proBNP testing in pregnant patients with SARS-CoV-2 infection can be a relatively important marker to be taken into consideration when it comes to the management, treatment and outcome of the cases, especially when it comes to women with associated cardiovascular risk factors. |
| first_indexed | 2024-03-10T21:46:58Z |
| format | Article |
| id | doaj.art-b97d9f10131a4d00b617fb9b18359792 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T21:46:58Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-b97d9f10131a4d00b617fb9b183597922023-11-19T14:13:47ZengMDPI AGDiagnostics2075-44182023-09-011319303210.3390/diagnostics13193032NT-proBNP—Possible Prognostic Marker in Pregnant Patients with Associated Cardiovascular Risk Factors and SARS-CoV-2 InfectionCarmen-Ioana Marta0Anca Laura Maghiari1Elena Bernad2Lavinia Stelea3Brenda Bernad4Lioara Boscu5Radu Neamtu6Adrian Gluhovschi7Mircea Diaconu8Catalin Dumitru9Bogdan Sorop10Katalin Babes11Faculty of Medicine and Pharmacy of Oradea, University of Oradea, 410087 Oradea, RomaniaDepartment I—Discipline of Anatomy and Embryology, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaClinic of Obstetrics and Gynecology, “Pius Brinzeu” County Clinical Emergency Hospital, 300723 Timisoara, RomaniaClinic of Obstetrics and Gynecology, “Pius Brinzeu” County Clinical Emergency Hospital, 300723 Timisoara, RomaniaDoctoral School, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaDoctoral School, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaClinic of Obstetrics and Gynecology, “Pius Brinzeu” County Clinical Emergency Hospital, 300723 Timisoara, RomaniaClinic of Obstetrics and Gynecology, “Pius Brinzeu” County Clinical Emergency Hospital, 300723 Timisoara, RomaniaClinic of Obstetrics and Gynecology, “Pius Brinzeu” County Clinical Emergency Hospital, 300723 Timisoara, RomaniaClinic of Obstetrics and Gynecology, “Pius Brinzeu” County Clinical Emergency Hospital, 300723 Timisoara, RomaniaClinic of Obstetrics and Gynecology, “Pius Brinzeu” County Clinical Emergency Hospital, 300723 Timisoara, RomaniaFaculty of Medicine and Pharmacy of Oradea, University of Oradea, 410087 Oradea, RomaniaBackground: N-terminal pro brain-type natriuretic peptide (NT-proBNP) is a practical biomarker in the clinical pathologies where the ventricle is under stress and particularly stretched in the general population. The study aims to compare the value of NT-proBNP and its importance in the prognosis and severity of the cases involving pregnant patients with SARS-CoV-2 infection and cardiovascular risk factors to those of low-risk pregnant patients, mainly by analysing their symptoms, administered medication, days of hospitalization and severity of the viral disease. Methods: The study included a total of eighty-three pregnant patients who underwent natural birth or caesarean section at out hospital. NT-proBNP levels were analyzed at hospital admission as a potential cardiovascular marker. A comparative analysis was performed between pregnant patients with cardiovascular risk factors and pregnant patients without cardiovascular risk factors regarding NT-proBNP values. Results: Pregnant patients with SARS-CoV-2 infection and cardiovascular risk factors had higher values of NT-proBNP in comparison to pregnant patients without cardiovascular risk factors. Conclusions: NT-proBNP testing in pregnant patients with SARS-CoV-2 infection can be a relatively important marker to be taken into consideration when it comes to the management, treatment and outcome of the cases, especially when it comes to women with associated cardiovascular risk factors.https://www.mdpi.com/2075-4418/13/19/3032NT-proBNPSARS-CoV-2cardiovascular diseasespregnancy complicationsperipartum cardiomiopathy |
| spellingShingle | Carmen-Ioana Marta Anca Laura Maghiari Elena Bernad Lavinia Stelea Brenda Bernad Lioara Boscu Radu Neamtu Adrian Gluhovschi Mircea Diaconu Catalin Dumitru Bogdan Sorop Katalin Babes NT-proBNP—Possible Prognostic Marker in Pregnant Patients with Associated Cardiovascular Risk Factors and SARS-CoV-2 Infection Diagnostics NT-proBNP SARS-CoV-2 cardiovascular diseases pregnancy complications peripartum cardiomiopathy |
| title | NT-proBNP—Possible Prognostic Marker in Pregnant Patients with Associated Cardiovascular Risk Factors and SARS-CoV-2 Infection |
| title_full | NT-proBNP—Possible Prognostic Marker in Pregnant Patients with Associated Cardiovascular Risk Factors and SARS-CoV-2 Infection |
| title_fullStr | NT-proBNP—Possible Prognostic Marker in Pregnant Patients with Associated Cardiovascular Risk Factors and SARS-CoV-2 Infection |
| title_full_unstemmed | NT-proBNP—Possible Prognostic Marker in Pregnant Patients with Associated Cardiovascular Risk Factors and SARS-CoV-2 Infection |
| title_short | NT-proBNP—Possible Prognostic Marker in Pregnant Patients with Associated Cardiovascular Risk Factors and SARS-CoV-2 Infection |
| title_sort | nt probnp possible prognostic marker in pregnant patients with associated cardiovascular risk factors and sars cov 2 infection |
| topic | NT-proBNP SARS-CoV-2 cardiovascular diseases pregnancy complications peripartum cardiomiopathy |
| url | https://www.mdpi.com/2075-4418/13/19/3032 |
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