Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex
This paper aimed to assess language development in infants and toddlers with tuberous sclerosis complex (TSC) and epilepsy, which increase the risk of autism spectrum disorder. We assessed language development in 61 patients with TSC at 8–36 months using a standardized Speech Development and Communi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/15/4564 |
| _version_ | 1797432861184229376 |
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| author | Małgorzata Foryś-Basiejko Katarzyna Kotulska Agnieszka Maryniak Agata Siłuszyk Monika Szkop Julita Borkowska Monika Sugalska Jagoda Głowacka-Walas Sergiusz Jóźwiak |
| author_facet | Małgorzata Foryś-Basiejko Katarzyna Kotulska Agnieszka Maryniak Agata Siłuszyk Monika Szkop Julita Borkowska Monika Sugalska Jagoda Głowacka-Walas Sergiusz Jóźwiak |
| author_sort | Małgorzata Foryś-Basiejko |
| collection | DOAJ |
| description | This paper aimed to assess language development in infants and toddlers with tuberous sclerosis complex (TSC) and epilepsy, which increase the risk of autism spectrum disorder. We assessed language development in 61 patients with TSC at 8–36 months using a standardized Speech Development and Communication Inventory tool. The results showed differences in outcomes due to the duration of the seizures and the number of drugs (pFDR = 0.007 **—pFDR = 0.037 *). Children with TSC with longer epilepsy duration and receiving more antiepileptic drugs have a greater risk of language development delay. |
| first_indexed | 2024-03-09T10:07:47Z |
| format | Article |
| id | doaj.art-b97e53a247744ae99a25a49a9e658c28 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T10:07:47Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-b97e53a247744ae99a25a49a9e658c282023-12-01T23:00:07ZengMDPI AGJournal of Clinical Medicine2077-03832022-08-011115456410.3390/jcm11154564Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis ComplexMałgorzata Foryś-Basiejko0Katarzyna Kotulska1Agnieszka Maryniak2Agata Siłuszyk3Monika Szkop4Julita Borkowska5Monika Sugalska6Jagoda Głowacka-Walas7Sergiusz Jóźwiak8Department of Child Clinical Psychology and Family, Faculty of Psychology, University of Warsaw, 00-183 Warszawa, PolandDepartment of Neurology and Epileptology, The Children’s Memorial Health Institute, 04-736 Warszawa, PolandDepartment of Child Clinical Psychology and Family, Faculty of Psychology, University of Warsaw, 00-183 Warszawa, PolandDepartment of Pediatric Neurology, Medical University of Warsaw, 02-091 Warszawa, PolandDepartment of Neurology and Epileptology, The Children’s Memorial Health Institute, 04-736 Warszawa, PolandDepartment of Neurology and Epileptology, The Children’s Memorial Health Institute, 04-736 Warszawa, PolandDepartment of Pediatric Neurology, Medical University of Warsaw, 02-091 Warszawa, PolandInstitute of Computer Science, Warsaw University of Technology, 00-665 Warszawa, PolandDepartment of Pediatric Neurology, Medical University of Warsaw, 02-091 Warszawa, PolandThis paper aimed to assess language development in infants and toddlers with tuberous sclerosis complex (TSC) and epilepsy, which increase the risk of autism spectrum disorder. We assessed language development in 61 patients with TSC at 8–36 months using a standardized Speech Development and Communication Inventory tool. The results showed differences in outcomes due to the duration of the seizures and the number of drugs (pFDR = 0.007 **—pFDR = 0.037 *). Children with TSC with longer epilepsy duration and receiving more antiepileptic drugs have a greater risk of language development delay.https://www.mdpi.com/2077-0383/11/15/4564language developmenttuberous sclerosis complexepilepsyvocabularygesture production |
| spellingShingle | Małgorzata Foryś-Basiejko Katarzyna Kotulska Agnieszka Maryniak Agata Siłuszyk Monika Szkop Julita Borkowska Monika Sugalska Jagoda Głowacka-Walas Sergiusz Jóźwiak Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex Journal of Clinical Medicine language development tuberous sclerosis complex epilepsy vocabulary gesture production |
| title | Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex |
| title_full | Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex |
| title_fullStr | Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex |
| title_full_unstemmed | Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex |
| title_short | Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex |
| title_sort | epilepsy and language development in 8 36 month old toddlers with tuberous sclerosis complex |
| topic | language development tuberous sclerosis complex epilepsy vocabulary gesture production |
| url | https://www.mdpi.com/2077-0383/11/15/4564 |
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