KDM4 Involvement in Breast Cancer and Possible Therapeutic Approaches

KDM4 Involvement in Breast Cancer and Possible Therapeutic Approaches

Breast cancer (BC) is the second leading cause of cancer death in women, although recent scientific and technological achievements have led to significant improvements in progression-free disease and overall survival of patients. Genetic mutations and epigenetic modifications play a critical role in...

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Bibliographic Details
Main Authors: Benluvankar Varghese, Nunzio Del Gaudio, Gilda Cobellis, Lucia Altucci, Angela Nebbioso
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
epigenetics
histone demethylation
KDM4 inhibitors
JMJD2
KDM4
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.750315/full

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