Evaluation of a strategy for enrolling the families of critically ill patients in research using limited human resources.
RATIONALE:Clinical trials of interventions aimed at the families of intensive care unit (ICU) patients have proliferated but recruitment for these trials can be challenging. OBJECTIVES:To evaluate a strategy for recruiting families of patients currently being treated in an ICU using limited human re...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5444627?pdf=render |
| _version_ | 1818142320536584192 |
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| author | Alison E Turnbull Mohamed D Hashem Anahita Rabiee An To Caroline M Chessare Dale M Needham |
| author_facet | Alison E Turnbull Mohamed D Hashem Anahita Rabiee An To Caroline M Chessare Dale M Needham |
| author_sort | Alison E Turnbull |
| collection | DOAJ |
| description | RATIONALE:Clinical trials of interventions aimed at the families of intensive care unit (ICU) patients have proliferated but recruitment for these trials can be challenging. OBJECTIVES:To evaluate a strategy for recruiting families of patients currently being treated in an ICU using limited human resources and time-varying daily screening over 7 consecutive days. METHODS:We screened the Johns Hopkins Hospital medical ICU census 7 days per week to identify eligible family members. We then made daily, in-person attempts to enroll eligible families during a time-varying 2-hour enrollment period until families declined participation, consented, or were no longer eligible. MEASUREMENTS AND MAIN RESULTS:The primary outcome was the proportion of eligible patients for whom ≥1 family member was enrolled. Secondary outcomes included enrollment of legal healthcare proxies, the consent rate among families approached for enrollment, and success rates for recruiting at different times during the day and week. Among 284 eligible patients, 108 (38%, 95% CI 32%-44%) had ≥1 family member enrolled, and 75 (26%, 95% CI 21%-32%) had their legal healthcare proxy enrolled. Among 117 family members asked to participate, 108 (92%, 95% CI 86%-96%) were enrolled. Patients with versus without an enrolled proxy were more likely to be white (44% vs. 30%, P = .02), live in a zip code with a median income of ≥$100,000 (15% vs. 5%, P = .01), be mechanically ventilated (63% vs. 47%, P = .01), die in the ICU (19% vs. 9%, P = .03), and to have longer ICU stays (median 5.0 vs. 1.8 days, P<.001). Day of the week and time of day were not associated with family presence in the ICU or consent rate. CONCLUSIONS:Family members were recruited for more than one third of eligible patients, and >90% of approached consented to participate. There are important demographic differences between patients with vs without an enrolled family member. |
| first_indexed | 2024-12-11T11:13:54Z |
| format | Article |
| id | doaj.art-b97fdb3643ed47bf903fe7232f40b573 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-11T11:13:54Z |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-b97fdb3643ed47bf903fe7232f40b5732022-12-22T01:09:24ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01125e017774110.1371/journal.pone.0177741Evaluation of a strategy for enrolling the families of critically ill patients in research using limited human resources.Alison E TurnbullMohamed D HashemAnahita RabieeAn ToCaroline M ChessareDale M NeedhamRATIONALE:Clinical trials of interventions aimed at the families of intensive care unit (ICU) patients have proliferated but recruitment for these trials can be challenging. OBJECTIVES:To evaluate a strategy for recruiting families of patients currently being treated in an ICU using limited human resources and time-varying daily screening over 7 consecutive days. METHODS:We screened the Johns Hopkins Hospital medical ICU census 7 days per week to identify eligible family members. We then made daily, in-person attempts to enroll eligible families during a time-varying 2-hour enrollment period until families declined participation, consented, or were no longer eligible. MEASUREMENTS AND MAIN RESULTS:The primary outcome was the proportion of eligible patients for whom ≥1 family member was enrolled. Secondary outcomes included enrollment of legal healthcare proxies, the consent rate among families approached for enrollment, and success rates for recruiting at different times during the day and week. Among 284 eligible patients, 108 (38%, 95% CI 32%-44%) had ≥1 family member enrolled, and 75 (26%, 95% CI 21%-32%) had their legal healthcare proxy enrolled. Among 117 family members asked to participate, 108 (92%, 95% CI 86%-96%) were enrolled. Patients with versus without an enrolled proxy were more likely to be white (44% vs. 30%, P = .02), live in a zip code with a median income of ≥$100,000 (15% vs. 5%, P = .01), be mechanically ventilated (63% vs. 47%, P = .01), die in the ICU (19% vs. 9%, P = .03), and to have longer ICU stays (median 5.0 vs. 1.8 days, P<.001). Day of the week and time of day were not associated with family presence in the ICU or consent rate. CONCLUSIONS:Family members were recruited for more than one third of eligible patients, and >90% of approached consented to participate. There are important demographic differences between patients with vs without an enrolled family member.http://europepmc.org/articles/PMC5444627?pdf=render |
| spellingShingle | Alison E Turnbull Mohamed D Hashem Anahita Rabiee An To Caroline M Chessare Dale M Needham Evaluation of a strategy for enrolling the families of critically ill patients in research using limited human resources. PLoS ONE |
| title | Evaluation of a strategy for enrolling the families of critically ill patients in research using limited human resources. |
| title_full | Evaluation of a strategy for enrolling the families of critically ill patients in research using limited human resources. |
| title_fullStr | Evaluation of a strategy for enrolling the families of critically ill patients in research using limited human resources. |
| title_full_unstemmed | Evaluation of a strategy for enrolling the families of critically ill patients in research using limited human resources. |
| title_short | Evaluation of a strategy for enrolling the families of critically ill patients in research using limited human resources. |
| title_sort | evaluation of a strategy for enrolling the families of critically ill patients in research using limited human resources |
| url | http://europepmc.org/articles/PMC5444627?pdf=render |
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