Feeding spray-dried plasma to broilers early in life improved their intestinal development, immunity and performance irrespective of mycotoxins in feed
IntroductionFungi that produce mycotoxins can grow on certain food products, such as grains and feed, and can cause a variety of health issues if consumed by animals, including chickens. The use of spray-dried plasma (SDP) is one strategy for combating the health problems caused by mycotoxins.Materi...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2023.1321351/full |
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| author | Gabriela Gómez-Verduzco José Arce-Menocal Carlos López-Coello Ernesto Avila-González Claudia C. Márquez-Mota Javier Polo Luis Rangel |
| author_facet | Gabriela Gómez-Verduzco José Arce-Menocal Carlos López-Coello Ernesto Avila-González Claudia C. Márquez-Mota Javier Polo Luis Rangel |
| author_sort | Gabriela Gómez-Verduzco |
| collection | DOAJ |
| description | IntroductionFungi that produce mycotoxins can grow on certain food products, such as grains and feed, and can cause a variety of health issues if consumed by animals, including chickens. The use of spray-dried plasma (SDP) is one strategy for combating the health problems caused by mycotoxins.Materials and methodsIn the present study, Ross 308 chickens (n = 960) were divided into four treatment groups. T1 group was given a control diet (corn–soybean meal), T2 group was given a control diet +2% SDP, T3 group was given a control diet +2% SDP + mixture mycotoxins and T4 group was givena control diet + mycotoxin mixture.ResultsThe presence of SDP resulted in weight gain and decreased feed efficiency, whereas mycotoxins resulted in weight loss and increased feed efficiency. SDP increased the thymus’ relative weight. The presence of mycotoxins increased the heterophile/lymphocyte ratio. The presence of mycotoxins reduced the production of IL-2 and macrophage inflammatory protein-3 Alpha (MIP-3a), whereas the presence of SDP increased the production of macrophage colony-stimulating Factor (M-CSF). SDP resulted in higher IgA concentrations in the intestinal and tracheal washes than mycotoxin. Finally, adding SDP to broiler diets boosts weight gain, feed efficiency, and immune system development.DiscussionOur results provide information supporting that SDP is a promising tool for improving poultry immunity and performance. |
| first_indexed | 2024-03-08T14:48:16Z |
| format | Article |
| id | doaj.art-b98244086b114381891506f288c4e09f |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-03-08T14:48:16Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-b98244086b114381891506f288c4e09f2024-01-11T05:28:44ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692024-01-011010.3389/fvets.2023.13213511321351Feeding spray-dried plasma to broilers early in life improved their intestinal development, immunity and performance irrespective of mycotoxins in feedGabriela Gómez-Verduzco0José Arce-Menocal1Carlos López-Coello2Ernesto Avila-González3Claudia C. Márquez-Mota4Javier Polo5Luis Rangel6Departamento de Medicina y Zootecnia de Aves, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad de México, MexicoDepartamento de Producción avícola, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo, Morelia, MexicoDepartamento de Medicina y Zootecnia de Aves, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad de México, MexicoCentro de Enseñanza, Investigación y Extensión en Producción Avícola CEIEPAv, Tláhuac, MexicoDepartamento de Nutrición Animal y Bioquímica, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad de México, MexicoAPC LLC, Ankeny, IA, United StatesAPC LLC, Ankeny, IA, United StatesIntroductionFungi that produce mycotoxins can grow on certain food products, such as grains and feed, and can cause a variety of health issues if consumed by animals, including chickens. The use of spray-dried plasma (SDP) is one strategy for combating the health problems caused by mycotoxins.Materials and methodsIn the present study, Ross 308 chickens (n = 960) were divided into four treatment groups. T1 group was given a control diet (corn–soybean meal), T2 group was given a control diet +2% SDP, T3 group was given a control diet +2% SDP + mixture mycotoxins and T4 group was givena control diet + mycotoxin mixture.ResultsThe presence of SDP resulted in weight gain and decreased feed efficiency, whereas mycotoxins resulted in weight loss and increased feed efficiency. SDP increased the thymus’ relative weight. The presence of mycotoxins increased the heterophile/lymphocyte ratio. The presence of mycotoxins reduced the production of IL-2 and macrophage inflammatory protein-3 Alpha (MIP-3a), whereas the presence of SDP increased the production of macrophage colony-stimulating Factor (M-CSF). SDP resulted in higher IgA concentrations in the intestinal and tracheal washes than mycotoxin. Finally, adding SDP to broiler diets boosts weight gain, feed efficiency, and immune system development.DiscussionOur results provide information supporting that SDP is a promising tool for improving poultry immunity and performance.https://www.frontiersin.org/articles/10.3389/fvets.2023.1321351/fullfeed additiveintoxicationpoultryhealthnutritiongrowth |
| spellingShingle | Gabriela Gómez-Verduzco José Arce-Menocal Carlos López-Coello Ernesto Avila-González Claudia C. Márquez-Mota Javier Polo Luis Rangel Feeding spray-dried plasma to broilers early in life improved their intestinal development, immunity and performance irrespective of mycotoxins in feed Frontiers in Veterinary Science feed additive intoxication poultry health nutrition growth |
| title | Feeding spray-dried plasma to broilers early in life improved their intestinal development, immunity and performance irrespective of mycotoxins in feed |
| title_full | Feeding spray-dried plasma to broilers early in life improved their intestinal development, immunity and performance irrespective of mycotoxins in feed |
| title_fullStr | Feeding spray-dried plasma to broilers early in life improved their intestinal development, immunity and performance irrespective of mycotoxins in feed |
| title_full_unstemmed | Feeding spray-dried plasma to broilers early in life improved their intestinal development, immunity and performance irrespective of mycotoxins in feed |
| title_short | Feeding spray-dried plasma to broilers early in life improved their intestinal development, immunity and performance irrespective of mycotoxins in feed |
| title_sort | feeding spray dried plasma to broilers early in life improved their intestinal development immunity and performance irrespective of mycotoxins in feed |
| topic | feed additive intoxication poultry health nutrition growth |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2023.1321351/full |
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