Case reports Unusual location of tuberculosis in the course of tumor necrosis factor α inhibitor therapy
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis complex mycobacteria. Extrapulmonary tuberculosis usually develops more than two years after infection or many years later. Factors favoring onset of the disease are malnutrition, older age, renal failure, diabetes, cancer,...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2015-08-01
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| Series: | Rheumatology |
| Subjects: | |
| Online Access: | http://www.termedia.pl/Case-reports-Unusual-location-of-tuberculosis-in-the-course-of-tumor-necrosis-factor-inhibitor-therapy,18,25554,1,1.html |
| _version_ | 1828523455162613760 |
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| author | Agnieszka Bielewicz-Zielińska Jan Brzezicki Marcin Rymko Sławomir Jeka |
| author_facet | Agnieszka Bielewicz-Zielińska Jan Brzezicki Marcin Rymko Sławomir Jeka |
| author_sort | Agnieszka Bielewicz-Zielińska |
| collection | DOAJ |
| description | Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis complex mycobacteria. Extrapulmonary tuberculosis usually develops more than two years after infection or many years later. Factors favoring onset of the disease are malnutrition, older age, renal failure, diabetes, cancer, immunosuppression and biological treatment, e.g. tumor necrosis factor α (TNF-α) inhibitors. The paper presents a case of a 56-year-old patient with ankylosing spondylitis treated with infliximab, diagnosed with tuberculosis of the spleen. The unusual location and uncharacteristic symptoms created a lot of diagnostic difficulties, particularly as during qualification for biological treatment tests are performed to exclude infection with Mycobacterium tuberculosis . Pharmacological treatment of tuberculosis is typical, but in the case of tuberculosis of the spleen, splenectomy also is a method of treatment. The decision was made to implement pharmacological treatment, which proved to be effective, so the patient avoided surgery. |
| first_indexed | 2024-12-11T20:29:11Z |
| format | Article |
| id | doaj.art-b983c31562494fe49ab7c107f971f734 |
| institution | Directory Open Access Journal |
| issn | 0034-6233 2084-9834 |
| language | English |
| last_indexed | 2024-12-11T20:29:11Z |
| publishDate | 2015-08-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Rheumatology |
| spelling | doaj.art-b983c31562494fe49ab7c107f971f7342022-12-22T00:51:53ZengTermedia Publishing HouseRheumatology0034-62332084-98342015-08-0153316116410.5114/reum.2015.5313925554Case reports Unusual location of tuberculosis in the course of tumor necrosis factor α inhibitor therapyAgnieszka Bielewicz-ZielińskaJan BrzezickiMarcin RymkoSławomir JekaTuberculosis is an infectious disease caused by Mycobacterium tuberculosis complex mycobacteria. Extrapulmonary tuberculosis usually develops more than two years after infection or many years later. Factors favoring onset of the disease are malnutrition, older age, renal failure, diabetes, cancer, immunosuppression and biological treatment, e.g. tumor necrosis factor α (TNF-α) inhibitors. The paper presents a case of a 56-year-old patient with ankylosing spondylitis treated with infliximab, diagnosed with tuberculosis of the spleen. The unusual location and uncharacteristic symptoms created a lot of diagnostic difficulties, particularly as during qualification for biological treatment tests are performed to exclude infection with Mycobacterium tuberculosis . Pharmacological treatment of tuberculosis is typical, but in the case of tuberculosis of the spleen, splenectomy also is a method of treatment. The decision was made to implement pharmacological treatment, which proved to be effective, so the patient avoided surgery.http://www.termedia.pl/Case-reports-Unusual-location-of-tuberculosis-in-the-course-of-tumor-necrosis-factor-inhibitor-therapy,18,25554,1,1.htmltuberculosis <i>Mycobacterium tuberculosis</i> anti-TNF |
| spellingShingle | Agnieszka Bielewicz-Zielińska Jan Brzezicki Marcin Rymko Sławomir Jeka Case reports Unusual location of tuberculosis in the course of tumor necrosis factor α inhibitor therapy Rheumatology tuberculosis <i>Mycobacterium tuberculosis</i> anti-TNF |
| title | Case reports Unusual location of tuberculosis in the course of tumor necrosis factor α inhibitor therapy |
| title_full | Case reports Unusual location of tuberculosis in the course of tumor necrosis factor α inhibitor therapy |
| title_fullStr | Case reports Unusual location of tuberculosis in the course of tumor necrosis factor α inhibitor therapy |
| title_full_unstemmed | Case reports Unusual location of tuberculosis in the course of tumor necrosis factor α inhibitor therapy |
| title_short | Case reports Unusual location of tuberculosis in the course of tumor necrosis factor α inhibitor therapy |
| title_sort | case reports unusual location of tuberculosis in the course of tumor necrosis factor α inhibitor therapy |
| topic | tuberculosis <i>Mycobacterium tuberculosis</i> anti-TNF |
| url | http://www.termedia.pl/Case-reports-Unusual-location-of-tuberculosis-in-the-course-of-tumor-necrosis-factor-inhibitor-therapy,18,25554,1,1.html |
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