Commercial hydrogel product for drug delivery based on route of administration

Hydrogels are hydrophilic, three-dimensional, cross-linked polymers that absorb significant amounts of biological fluids or water. Hydrogels possess several favorable properties, including flexibility, stimulus-responsiveness, versatility, and structural composition. They can be categorized accordin...

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Main Authors: Amin Raeisi, Fatemeh Farjadian
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2024.1336717/full
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author Amin Raeisi
Amin Raeisi
Fatemeh Farjadian
author_facet Amin Raeisi
Amin Raeisi
Fatemeh Farjadian
author_sort Amin Raeisi
collection DOAJ
description Hydrogels are hydrophilic, three-dimensional, cross-linked polymers that absorb significant amounts of biological fluids or water. Hydrogels possess several favorable properties, including flexibility, stimulus-responsiveness, versatility, and structural composition. They can be categorized according to their sources, synthesis route, response to stimulus, and application. Controlling the cross-link density matrix and the hydrogels’ attraction to water while they’re swelling makes it easy to change their porous structure, which makes them ideal for drug delivery. Hydrogel in drug delivery can be achieved by various routes involving injectable, oral, buccal, vaginal, ocular, and transdermal administration routes. The hydrogel market is expected to grow from its 2019 valuation of USD 22.1 billion to USD 31.4 billion by 2027. Commercial hydrogels are helpful for various drug delivery applications, such as transdermal patches with controlled release characteristics, stimuli-responsive hydrogels for oral administration, and localized delivery via parenteral means. Here, we are mainly focused on the commercial hydrogel products used for drug delivery based on the described route of administration.
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spelling doaj.art-b9847bf3de0a4dc3abe88d32e1ab44742024-02-27T04:13:56ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462024-02-011210.3389/fchem.2024.13367171336717Commercial hydrogel product for drug delivery based on route of administrationAmin Raeisi0Amin Raeisi1Fatemeh Farjadian2Pharmaceutical Sciences Research Center, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, IranPharmaceutical Sciences Research Center, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, IranHydrogels are hydrophilic, three-dimensional, cross-linked polymers that absorb significant amounts of biological fluids or water. Hydrogels possess several favorable properties, including flexibility, stimulus-responsiveness, versatility, and structural composition. They can be categorized according to their sources, synthesis route, response to stimulus, and application. Controlling the cross-link density matrix and the hydrogels’ attraction to water while they’re swelling makes it easy to change their porous structure, which makes them ideal for drug delivery. Hydrogel in drug delivery can be achieved by various routes involving injectable, oral, buccal, vaginal, ocular, and transdermal administration routes. The hydrogel market is expected to grow from its 2019 valuation of USD 22.1 billion to USD 31.4 billion by 2027. Commercial hydrogels are helpful for various drug delivery applications, such as transdermal patches with controlled release characteristics, stimuli-responsive hydrogels for oral administration, and localized delivery via parenteral means. Here, we are mainly focused on the commercial hydrogel products used for drug delivery based on the described route of administration.https://www.frontiersin.org/articles/10.3389/fchem.2024.1336717/fullhydrogeldrug deliverycommercial productsroutes of administrationbuccaltransdermal
spellingShingle Amin Raeisi
Amin Raeisi
Fatemeh Farjadian
Commercial hydrogel product for drug delivery based on route of administration
Frontiers in Chemistry
hydrogel
drug delivery
commercial products
routes of administration
buccal
transdermal
title Commercial hydrogel product for drug delivery based on route of administration
title_full Commercial hydrogel product for drug delivery based on route of administration
title_fullStr Commercial hydrogel product for drug delivery based on route of administration
title_full_unstemmed Commercial hydrogel product for drug delivery based on route of administration
title_short Commercial hydrogel product for drug delivery based on route of administration
title_sort commercial hydrogel product for drug delivery based on route of administration
topic hydrogel
drug delivery
commercial products
routes of administration
buccal
transdermal
url https://www.frontiersin.org/articles/10.3389/fchem.2024.1336717/full
work_keys_str_mv AT aminraeisi commercialhydrogelproductfordrugdeliverybasedonrouteofadministration
AT aminraeisi commercialhydrogelproductfordrugdeliverybasedonrouteofadministration
AT fatemehfarjadian commercialhydrogelproductfordrugdeliverybasedonrouteofadministration