The anterior cingulate cortex contributes to the analgesic rather than the anxiolytic effects of duloxetine in chronic pain-induced anxiety

The anterior cingulate cortex contributes to the analgesic rather than the anxiolytic effects of duloxetine in chronic pain-induced anxiety

Mood disorders, such as anxiety and depression, are commonly found in people suffering from chronic pain. Serotonin–norepinephrine reuptake inhibitors (SNRIs) are potential in alleviating chronic pain and are the first-line option for anxiety disorder. The anterior cingulate cortex (ACC) plays a vit...

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Bibliographic Details
Main Authors: Chenglin Li, Kaiji Ni, Meiru Qi, Jie Li, Kexin Yang, Yanli Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Neuroscience
Subjects:
duloxetine
chronic pain
anxiety
anterior cingulate cortex
fiber photometry
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.992130/full

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