COVID-19 outbreak response at a nursing hospital in South Korea in the post-vaccination era, including an estimation of the effectiveness of the first shot of the Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1-S)
Objectives We descriptively reviewed a coronavirus disease 2019 (COVID-19) outbreak at a nursing hospital in Gyeonggi Province (South Korea) and assessed the effectiveness of the first dose of the Oxford-AstraZeneca vaccine in a real-world population. Methods The general process of the epidemiologic...
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| Format: | Article |
| Language: | English |
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Korea Disease Control and Prevention Agency
2022-04-01
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| Series: | Osong Public Health and Research Perspectives |
| Subjects: | |
| Online Access: | http://ophrp.org/upload/pdf/j-phrp-2021-0262.pdf |
| _version_ | 1797725559157948416 |
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| author | Chanhee Kim Geon Kang Sun Gu Kang Heeyoung Lee |
| author_facet | Chanhee Kim Geon Kang Sun Gu Kang Heeyoung Lee |
| author_sort | Chanhee Kim |
| collection | DOAJ |
| description | Objectives We descriptively reviewed a coronavirus disease 2019 (COVID-19) outbreak at a nursing hospital in Gyeonggi Province (South Korea) and assessed the effectiveness of the first dose of the Oxford-AstraZeneca vaccine in a real-world population. Methods The general process of the epidemiological investigation included a public health intervention. The relative risk (RR) of vaccinated and unvaccinated groups was calculated and compared to confirm the risk of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, and vaccine effectiveness was evaluated based on the calculated RR. Results The population at risk was confined to ward E among 8 wards of Hospital X, where the outbreak occurred. This population comprised 55 people, including 39 patients, 12 nurses, and 4 caregivers, and 19 cases were identified. The RR between the vaccinated and unvaccinated groups was 0.04, resulting in a vaccine effectiveness of 95.3%. The vaccination rate of the non-patients in ward E was the lowest in the entire hospital, whereas the overall vaccination rate of the combined patient and non-patient groups in ward E was the third lowest. Conclusion The first dose of the Oxford-AstraZeneca vaccine (ChAdOx1-S) was effective in preventing SARS-CoV-2 infection. To prevent COVID-19 outbreaks in medical facilities, it is important to prioritize the vaccination of healthcare providers. |
| first_indexed | 2024-03-12T10:33:00Z |
| format | Article |
| id | doaj.art-b9852ab1b6b045f39ae61102c0e45488 |
| institution | Directory Open Access Journal |
| issn | 2210-9099 2210-9110 |
| language | English |
| last_indexed | 2024-03-12T10:33:00Z |
| publishDate | 2022-04-01 |
| publisher | Korea Disease Control and Prevention Agency |
| record_format | Article |
| series | Osong Public Health and Research Perspectives |
| spelling | doaj.art-b9852ab1b6b045f39ae61102c0e454882023-09-02T09:06:24ZengKorea Disease Control and Prevention AgencyOsong Public Health and Research Perspectives2210-90992210-91102022-04-0113211412210.24171/j.phrp.2021.0262659COVID-19 outbreak response at a nursing hospital in South Korea in the post-vaccination era, including an estimation of the effectiveness of the first shot of the Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1-S)Chanhee Kim0Geon Kang1Sun Gu Kang2Heeyoung Lee3 Infectious Disease Control Center, Gyeonggi Provincial Government, Suwon, Korea Infectious Disease Control Center, Gyeonggi Provincial Government, Suwon, Korea Infectious Disease Control Center, Gyeonggi Provincial Government, Suwon, Korea Center for Preventive Medicine and Public Health, Seoul National University Bundang Hospital, Seongnam, KoreaObjectives We descriptively reviewed a coronavirus disease 2019 (COVID-19) outbreak at a nursing hospital in Gyeonggi Province (South Korea) and assessed the effectiveness of the first dose of the Oxford-AstraZeneca vaccine in a real-world population. Methods The general process of the epidemiological investigation included a public health intervention. The relative risk (RR) of vaccinated and unvaccinated groups was calculated and compared to confirm the risk of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, and vaccine effectiveness was evaluated based on the calculated RR. Results The population at risk was confined to ward E among 8 wards of Hospital X, where the outbreak occurred. This population comprised 55 people, including 39 patients, 12 nurses, and 4 caregivers, and 19 cases were identified. The RR between the vaccinated and unvaccinated groups was 0.04, resulting in a vaccine effectiveness of 95.3%. The vaccination rate of the non-patients in ward E was the lowest in the entire hospital, whereas the overall vaccination rate of the combined patient and non-patient groups in ward E was the third lowest. Conclusion The first dose of the Oxford-AstraZeneca vaccine (ChAdOx1-S) was effective in preventing SARS-CoV-2 infection. To prevent COVID-19 outbreaks in medical facilities, it is important to prioritize the vaccination of healthcare providers.http://ophrp.org/upload/pdf/j-phrp-2021-0262.pdfcovid-19disease outbreaksimmunizationsars-cov-2vaccinationvaccines |
| spellingShingle | Chanhee Kim Geon Kang Sun Gu Kang Heeyoung Lee COVID-19 outbreak response at a nursing hospital in South Korea in the post-vaccination era, including an estimation of the effectiveness of the first shot of the Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1-S) Osong Public Health and Research Perspectives covid-19 disease outbreaks immunization sars-cov-2 vaccination vaccines |
| title | COVID-19 outbreak response at a nursing hospital in South Korea in the post-vaccination era, including an estimation of the effectiveness of the first shot of the Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1-S) |
| title_full | COVID-19 outbreak response at a nursing hospital in South Korea in the post-vaccination era, including an estimation of the effectiveness of the first shot of the Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1-S) |
| title_fullStr | COVID-19 outbreak response at a nursing hospital in South Korea in the post-vaccination era, including an estimation of the effectiveness of the first shot of the Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1-S) |
| title_full_unstemmed | COVID-19 outbreak response at a nursing hospital in South Korea in the post-vaccination era, including an estimation of the effectiveness of the first shot of the Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1-S) |
| title_short | COVID-19 outbreak response at a nursing hospital in South Korea in the post-vaccination era, including an estimation of the effectiveness of the first shot of the Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1-S) |
| title_sort | covid 19 outbreak response at a nursing hospital in south korea in the post vaccination era including an estimation of the effectiveness of the first shot of the oxford astrazeneca covid 19 vaccine chadox1 s |
| topic | covid-19 disease outbreaks immunization sars-cov-2 vaccination vaccines |
| url | http://ophrp.org/upload/pdf/j-phrp-2021-0262.pdf |
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