Health-related quality of life and its determinants among patients with psoriasis at a referral hospital in Northwest Ethiopia
ObjectivesThis study assessed health-related quality of life (HRQoL) and its determinants among patients with psoriasis having follow-ups at the University of Gondar Comprehensive Specialized Hospital (UoGCSH).Design, setting, and participantsA cross-sectional institutional-based study was conducted...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1183685/full |
| _version_ | 1797780919927439360 |
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| author | Eyayaw Ashete Belachew Gashaw Sisay Chanie Eshetie Gizachew Ashenafi Kibret Sendekie |
| author_facet | Eyayaw Ashete Belachew Gashaw Sisay Chanie Eshetie Gizachew Ashenafi Kibret Sendekie |
| author_sort | Eyayaw Ashete Belachew |
| collection | DOAJ |
| description | ObjectivesThis study assessed health-related quality of life (HRQoL) and its determinants among patients with psoriasis having follow-ups at the University of Gondar Comprehensive Specialized Hospital (UoGCSH).Design, setting, and participantsA cross-sectional institutional-based study was conducted at the dermatologic clinic of UoGCSH from June to August 2022. Four hundred eligible patients with psoriasis were included in the study using a systematic random sampling technique.The main outcome measuredThe Dermatology Life Quality Index (DLQI) measurement scale was used to assess HRQoL. The relationship between HRQoL and independent predictor variables was investigated using bivariable and multivariate logistic regression analyses. Statistical significance was defined as a p-value of <0.05 at the 95% CI.ResultsOf the 422 study subjects approached, 400 respondents with psoriasis were included in the final analysis. The mean (±SD) age was 39.8 (±17.2) years, and 56% were women. The most commonly prescribed medications were topical corticosteroids (68.3 %). The mean (±SD) DLQI was 13.05 (7.82). More than three-fourths (78.5%) of the patients' HRQOL was affected, and its severity ranged from very large to extremely large. Being male (adjusted odd ratio) (AOR) = 0.373, 95% CI (0.171, 0.773), the use of alternative therapy (AOR) = 0.237, 95% CI (0.114, 0.494), duration of diseases (AOR) = 0.184, 95% CI (0.061, 0.557), duration on medication (AOR) =3.75, 95% CI (1.32, 10.73), presence of comorbidity (AOR) = 6.199, 95% CI (1.921, 20.00), and income were found to have a significant association with poor HRQoL.ConclusionPsoriasis patients had reduced HRQoL, which was lower than that of the normal population. The study identified that several variables contributed to this reduced HRQoL. Predictors that take into account interventions were essential for preserving patients' HRQoL. |
| first_indexed | 2024-03-12T23:50:36Z |
| format | Article |
| id | doaj.art-b98670e535344d0c964fb6c4fd18ec9f |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-03-12T23:50:36Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-b98670e535344d0c964fb6c4fd18ec9f2023-07-13T15:40:42ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-07-011010.3389/fmed.2023.11836851183685Health-related quality of life and its determinants among patients with psoriasis at a referral hospital in Northwest EthiopiaEyayaw Ashete Belachew0Gashaw Sisay Chanie1Eshetie Gizachew2Ashenafi Kibret Sendekie3Department of Clinical Pharmacy, School of Pharmacy, University of Gondar, Gondar, EthiopiaDepartment of Clinical Pharmacy, School of Pharmacy, University of Gondar, Gondar, EthiopiaDepartment of Information System, College of Informatics, University of Gondar, Gondar, EthiopiaDepartment of Clinical Pharmacy, School of Pharmacy, University of Gondar, Gondar, EthiopiaObjectivesThis study assessed health-related quality of life (HRQoL) and its determinants among patients with psoriasis having follow-ups at the University of Gondar Comprehensive Specialized Hospital (UoGCSH).Design, setting, and participantsA cross-sectional institutional-based study was conducted at the dermatologic clinic of UoGCSH from June to August 2022. Four hundred eligible patients with psoriasis were included in the study using a systematic random sampling technique.The main outcome measuredThe Dermatology Life Quality Index (DLQI) measurement scale was used to assess HRQoL. The relationship between HRQoL and independent predictor variables was investigated using bivariable and multivariate logistic regression analyses. Statistical significance was defined as a p-value of <0.05 at the 95% CI.ResultsOf the 422 study subjects approached, 400 respondents with psoriasis were included in the final analysis. The mean (±SD) age was 39.8 (±17.2) years, and 56% were women. The most commonly prescribed medications were topical corticosteroids (68.3 %). The mean (±SD) DLQI was 13.05 (7.82). More than three-fourths (78.5%) of the patients' HRQOL was affected, and its severity ranged from very large to extremely large. Being male (adjusted odd ratio) (AOR) = 0.373, 95% CI (0.171, 0.773), the use of alternative therapy (AOR) = 0.237, 95% CI (0.114, 0.494), duration of diseases (AOR) = 0.184, 95% CI (0.061, 0.557), duration on medication (AOR) =3.75, 95% CI (1.32, 10.73), presence of comorbidity (AOR) = 6.199, 95% CI (1.921, 20.00), and income were found to have a significant association with poor HRQoL.ConclusionPsoriasis patients had reduced HRQoL, which was lower than that of the normal population. The study identified that several variables contributed to this reduced HRQoL. Predictors that take into account interventions were essential for preserving patients' HRQoL.https://www.frontiersin.org/articles/10.3389/fmed.2023.1183685/fullpsoriasishealth-related quality of lifedeterminantsDermatology Life Quality IndexEthiopia |
| spellingShingle | Eyayaw Ashete Belachew Gashaw Sisay Chanie Eshetie Gizachew Ashenafi Kibret Sendekie Health-related quality of life and its determinants among patients with psoriasis at a referral hospital in Northwest Ethiopia Frontiers in Medicine psoriasis health-related quality of life determinants Dermatology Life Quality Index Ethiopia |
| title | Health-related quality of life and its determinants among patients with psoriasis at a referral hospital in Northwest Ethiopia |
| title_full | Health-related quality of life and its determinants among patients with psoriasis at a referral hospital in Northwest Ethiopia |
| title_fullStr | Health-related quality of life and its determinants among patients with psoriasis at a referral hospital in Northwest Ethiopia |
| title_full_unstemmed | Health-related quality of life and its determinants among patients with psoriasis at a referral hospital in Northwest Ethiopia |
| title_short | Health-related quality of life and its determinants among patients with psoriasis at a referral hospital in Northwest Ethiopia |
| title_sort | health related quality of life and its determinants among patients with psoriasis at a referral hospital in northwest ethiopia |
| topic | psoriasis health-related quality of life determinants Dermatology Life Quality Index Ethiopia |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1183685/full |
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