Generalized nuclear localization of retroelement transcripts

Abstract Background LINE-1s, Alus and SVAs are the only retrotransposition competent elements in humans. Their mobilization followed by insertional mutagenesis is often linked to disease. Apart from these rare integration events, accumulation of retrotransposition intermediates in the cytoplasm is p...

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Bibliographic Details
Main Authors: Simanti Das, Amanda E. Jones, John M. Abrams
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Mobile DNA
Subjects:
Online Access:https://doi.org/10.1186/s13100-022-00287-x