Generalized nuclear localization of retroelement transcripts
Abstract Background LINE-1s, Alus and SVAs are the only retrotransposition competent elements in humans. Their mobilization followed by insertional mutagenesis is often linked to disease. Apart from these rare integration events, accumulation of retrotransposition intermediates in the cytoplasm is p...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | Mobile DNA |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13100-022-00287-x |