Generalized nuclear localization of retroelement transcripts
Abstract Background LINE-1s, Alus and SVAs are the only retrotransposition competent elements in humans. Their mobilization followed by insertional mutagenesis is often linked to disease. Apart from these rare integration events, accumulation of retrotransposition intermediates in the cytoplasm is p...
Main Authors: | Simanti Das, Amanda E. Jones, John M. Abrams |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
|
Series: | Mobile DNA |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13100-022-00287-x |
Similar Items
-
Many Different LINE-1 Retroelements Are Activated in Bladder Cancer
by: Patcharawalai Whongsiri, et al.
Published: (2020-12-01) -
Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist
by: Kevin W Ng, et al.
Published: (2019-11-01) -
Expression of Retroelements in Cervical Cancer and Their Interplay with HPV Infection and Host Gene Expression
by: Gislaine Curty, et al.
Published: (2021-07-01) -
Implications of Endogenous Retroelements in the Etiopathogenesis of Systemic Lupus Erythematosus
by: Kennedy C. Ukadike, et al.
Published: (2021-02-01) -
Potential role of KRAB-ZFP binding and transcriptional states on DNA methylation of retroelements in human male germ cells
by: Kei Fukuda, et al.
Published: (2022-03-01)