Enriched environment ameliorates propagation of tau pathology and improves cognition in rat model of tauopathy

Enriched environment ameliorates propagation of tau pathology and improves cognition in rat model of tauopathy

IntroductionThe typical symptoms of Alzheimer’s disease (AD) are cognitive impairment, disrupted spatial orientation, behavioral and psychiatric abnormalities, and later motor deficits. Neuropathologically, AD is characterized by deposits of pathological forms of endogenous proteins – amyloid-β, and...

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Main Authors: Veronika Mate, Tomas Smolek, Zuzana Vince Kazmerova, Santosh Jadhav, Veronika Brezovakova, Bernadeta Jurkanin, Ivana Uhrinova, Neha Basheer, Norbert Zilka, Stanislav Katina, Petr Novak
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
histology
behavioral
enriched environment
propagation
seeding
tangle
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.935973/full

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