An overview of growth hormone therapy in pediatric cases documented in the Kabi International Growth Study (Pfizer International Growth Database)
The Kabi International Growth Study (KIGS) was first established in 1987 and is the largest pharmaco-epidemiological study of recombinant human growth hormone (rhGH). KIGS is aimed at evaluating long-term safety and treatment outcomes in pediatric subjects who received Genotropin rhGH therapy (Pfize...
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| Format: | Article |
| Language: | English |
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Korean Society of Pediatric Endocrinology
2024-02-01
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| Series: | Annals of Pediatric Endocrinology & Metabolism |
| Subjects: | |
| Online Access: | http://e-apem.org/upload/pdf/apem-2346206-103.pdf |
| _version_ | 1797266516717076480 |
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| author | Mitchell E. Geffner Michael B. Ranke Michael P. Wajnrajch for the Pfizer International Growth Database Strategic Executive Committee, Strategic Advisory Board, and International Board |
| author_facet | Mitchell E. Geffner Michael B. Ranke Michael P. Wajnrajch for the Pfizer International Growth Database Strategic Executive Committee, Strategic Advisory Board, and International Board |
| author_sort | Mitchell E. Geffner |
| collection | DOAJ |
| description | The Kabi International Growth Study (KIGS) was first established in 1987 and is the largest pharmaco-epidemiological study of recombinant human growth hormone (rhGH). KIGS is aimed at evaluating long-term safety and treatment outcomes in pediatric subjects who received Genotropin rhGH therapy (Pfizer, New York, NY, USA) as prescribed by physicians in real-world clinical practice settings. KIGS data have been used to answer multiple research questions related to growth, growth prediction, and growth hormone treatment, leading to the publication of 129 peer-reviewed manuscripts and 24 biannual reports, outcomes from 10 expert meetings, and 3 books. The KIGS has shown that rhGH is safe and increases both the short-term height gain and adult height in patients with GH deficiency (GHD) and multiple other non-GHD conditions associated with short stature. |
| first_indexed | 2024-04-25T01:01:56Z |
| format | Article |
| id | doaj.art-b98fa69e6d3a4b86b1e56a2cb6b1c35f |
| institution | Directory Open Access Journal |
| issn | 2287-1012 2287-1292 |
| language | English |
| last_indexed | 2024-04-25T01:01:56Z |
| publishDate | 2024-02-01 |
| publisher | Korean Society of Pediatric Endocrinology |
| record_format | Article |
| series | Annals of Pediatric Endocrinology & Metabolism |
| spelling | doaj.art-b98fa69e6d3a4b86b1e56a2cb6b1c35f2024-03-11T01:17:59ZengKorean Society of Pediatric EndocrinologyAnnals of Pediatric Endocrinology & Metabolism2287-10122287-12922024-02-0129131110.6065/apem.2346206.1031024An overview of growth hormone therapy in pediatric cases documented in the Kabi International Growth Study (Pfizer International Growth Database)Mitchell E. Geffner0Michael B. Ranke1Michael P. Wajnrajch2for the Pfizer International Growth Database Strategic Executive Committee, Strategic Advisory Board, and International Board The Saban Research Institute, Children’s Hospital Los Angeles, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA Department of Pediatric Endocrinology, University Children´s Hospital, Tübingen, Germany Pfizer Inc., New York, NY, USAThe Kabi International Growth Study (KIGS) was first established in 1987 and is the largest pharmaco-epidemiological study of recombinant human growth hormone (rhGH). KIGS is aimed at evaluating long-term safety and treatment outcomes in pediatric subjects who received Genotropin rhGH therapy (Pfizer, New York, NY, USA) as prescribed by physicians in real-world clinical practice settings. KIGS data have been used to answer multiple research questions related to growth, growth prediction, and growth hormone treatment, leading to the publication of 129 peer-reviewed manuscripts and 24 biannual reports, outcomes from 10 expert meetings, and 3 books. The KIGS has shown that rhGH is safe and increases both the short-term height gain and adult height in patients with GH deficiency (GHD) and multiple other non-GHD conditions associated with short stature.http://e-apem.org/upload/pdf/apem-2346206-103.pdfkabi international growth studypharmaco-epidemiological studyrecombinant human growth hormone |
| spellingShingle | Mitchell E. Geffner Michael B. Ranke Michael P. Wajnrajch for the Pfizer International Growth Database Strategic Executive Committee, Strategic Advisory Board, and International Board An overview of growth hormone therapy in pediatric cases documented in the Kabi International Growth Study (Pfizer International Growth Database) Annals of Pediatric Endocrinology & Metabolism kabi international growth study pharmaco-epidemiological study recombinant human growth hormone |
| title | An overview of growth hormone therapy in pediatric cases documented in the Kabi International Growth Study (Pfizer International Growth Database) |
| title_full | An overview of growth hormone therapy in pediatric cases documented in the Kabi International Growth Study (Pfizer International Growth Database) |
| title_fullStr | An overview of growth hormone therapy in pediatric cases documented in the Kabi International Growth Study (Pfizer International Growth Database) |
| title_full_unstemmed | An overview of growth hormone therapy in pediatric cases documented in the Kabi International Growth Study (Pfizer International Growth Database) |
| title_short | An overview of growth hormone therapy in pediatric cases documented in the Kabi International Growth Study (Pfizer International Growth Database) |
| title_sort | overview of growth hormone therapy in pediatric cases documented in the kabi international growth study pfizer international growth database |
| topic | kabi international growth study pharmaco-epidemiological study recombinant human growth hormone |
| url | http://e-apem.org/upload/pdf/apem-2346206-103.pdf |
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