Reliability and validity of the Amharic version of European Organization for Research and Treatment of cervical Cancer module for the assessment of health related quality of life in women with cervical cancer in Addis Ababa, Ethiopia
Abstract Background Cervical cancer is among the leading gynecological cancers affecting women worldwide. Maintenance and improvement of cervical cancer patients‘health related quality of life (HRQoL) is an important issue. The cervical cancer specific quality of life module of the European Organiza...
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| Format: | Article |
| Language: | English |
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BMC
2019-01-01
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| Series: | Health and Quality of Life Outcomes |
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| Online Access: | http://link.springer.com/article/10.1186/s12955-019-1089-x |
| _version_ | 1819039985036165120 |
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| author | Liya Teklu Araya Gebremedhin Beedemariam Gebretekle Girma Tekle Gebremariam Teferi Gedif Fenta |
| author_facet | Liya Teklu Araya Gebremedhin Beedemariam Gebretekle Girma Tekle Gebremariam Teferi Gedif Fenta |
| author_sort | Liya Teklu Araya |
| collection | DOAJ |
| description | Abstract Background Cervical cancer is among the leading gynecological cancers affecting women worldwide. Maintenance and improvement of cervical cancer patients‘health related quality of life (HRQoL) is an important issue. The cervical cancer specific quality of life module of the European Organization for Research and Treatment of Cancer (EORTC QLQ-CX24) is the most commonly used tool, however, it is not validated in Ethiopia. Hence, the present study aimed to assess the psychometric properties of the tool among Ethiopian cervical cancer patients. Methods Hospital based cross-sectional study was done in Tikur Anbessa Specialized Hospital (TASH), Addis Ababa, Ethiopia from January to February, 2018. The module was translated through forward-backward translation approach and pilot tested according to the EORTC Guidelines. One hundered and seventy one patients with confirmed cervical cancer were enrolled for the study. Amharic versions of EORTC QLQ-C30 and EORTC QLQ-CX24 were used to collect data along with socio-demographic and clinical characteristics. Descriptive statistics were used to assess socio-demographic and clinical characteristics of patients. The Psychometric properties of the EORTC QLQ-CX24 were evaluated in terms of acceptability, internal consistency, construct, concurrent and known group validity using SPSS version 22. Results One hundred seventy one cervical cancer patients were enrolled in the study, with a mean age of 52.15 ± 10.4 years. The EORTC QLQ-CX24 was found to be acceptable with high compliance and low missing responses. The Cronbach’s alpha ranged from 0.70–0.84, indicating the reliability of the scales. Convergent and discriminant validity in multitrait scaling analysis was adequate. The EORTC QLQ-C30 subscales and EORTC QLQ-CX24 subscales had a weak to strong correlation, indicating concurrent validity. The scales and single-item measures were able to discriminate between subgroups of patients differing with regard to performance status, cancer stage and treatment status, indicating clinical validity. Conclusion Amharic version of the EORTC QLQ-CX24 questionnaire is a valid and reliable tool and could be used for clinical and epidemiological cancer researches to study the HRQoL of patients with cervical cancer in Ethiopia. |
| first_indexed | 2024-12-21T09:01:54Z |
| format | Article |
| id | doaj.art-b99545d09d704c64a90f6f354e195b1c |
| institution | Directory Open Access Journal |
| issn | 1477-7525 |
| language | English |
| last_indexed | 2024-12-21T09:01:54Z |
| publishDate | 2019-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Health and Quality of Life Outcomes |
| spelling | doaj.art-b99545d09d704c64a90f6f354e195b1c2022-12-21T19:09:27ZengBMCHealth and Quality of Life Outcomes1477-75252019-01-011711710.1186/s12955-019-1089-xReliability and validity of the Amharic version of European Organization for Research and Treatment of cervical Cancer module for the assessment of health related quality of life in women with cervical cancer in Addis Ababa, EthiopiaLiya Teklu Araya0Gebremedhin Beedemariam Gebretekle1Girma Tekle Gebremariam2Teferi Gedif Fenta3Social and Administrative Pharmacy Unit, Department of Pharmaceutics and Social Pharmacy,School of Pharmacy, College of Health Sciences, Addis Ababa UniversitySocial and Administrative Pharmacy Unit, Department of Pharmaceutics and Social Pharmacy,School of Pharmacy, College of Health Sciences, Addis Ababa UniversityDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa UniversitySocial and Administrative Pharmacy Unit, Department of Pharmaceutics and Social Pharmacy,School of Pharmacy, College of Health Sciences, Addis Ababa UniversityAbstract Background Cervical cancer is among the leading gynecological cancers affecting women worldwide. Maintenance and improvement of cervical cancer patients‘health related quality of life (HRQoL) is an important issue. The cervical cancer specific quality of life module of the European Organization for Research and Treatment of Cancer (EORTC QLQ-CX24) is the most commonly used tool, however, it is not validated in Ethiopia. Hence, the present study aimed to assess the psychometric properties of the tool among Ethiopian cervical cancer patients. Methods Hospital based cross-sectional study was done in Tikur Anbessa Specialized Hospital (TASH), Addis Ababa, Ethiopia from January to February, 2018. The module was translated through forward-backward translation approach and pilot tested according to the EORTC Guidelines. One hundered and seventy one patients with confirmed cervical cancer were enrolled for the study. Amharic versions of EORTC QLQ-C30 and EORTC QLQ-CX24 were used to collect data along with socio-demographic and clinical characteristics. Descriptive statistics were used to assess socio-demographic and clinical characteristics of patients. The Psychometric properties of the EORTC QLQ-CX24 were evaluated in terms of acceptability, internal consistency, construct, concurrent and known group validity using SPSS version 22. Results One hundred seventy one cervical cancer patients were enrolled in the study, with a mean age of 52.15 ± 10.4 years. The EORTC QLQ-CX24 was found to be acceptable with high compliance and low missing responses. The Cronbach’s alpha ranged from 0.70–0.84, indicating the reliability of the scales. Convergent and discriminant validity in multitrait scaling analysis was adequate. The EORTC QLQ-C30 subscales and EORTC QLQ-CX24 subscales had a weak to strong correlation, indicating concurrent validity. The scales and single-item measures were able to discriminate between subgroups of patients differing with regard to performance status, cancer stage and treatment status, indicating clinical validity. Conclusion Amharic version of the EORTC QLQ-CX24 questionnaire is a valid and reliable tool and could be used for clinical and epidemiological cancer researches to study the HRQoL of patients with cervical cancer in Ethiopia.http://link.springer.com/article/10.1186/s12955-019-1089-xCervical CancerHRQoLValidationAmharic versionEORTC QLQ-CX24 |
| spellingShingle | Liya Teklu Araya Gebremedhin Beedemariam Gebretekle Girma Tekle Gebremariam Teferi Gedif Fenta Reliability and validity of the Amharic version of European Organization for Research and Treatment of cervical Cancer module for the assessment of health related quality of life in women with cervical cancer in Addis Ababa, Ethiopia Health and Quality of Life Outcomes Cervical Cancer HRQoL Validation Amharic version EORTC QLQ-CX24 |
| title | Reliability and validity of the Amharic version of European Organization for Research and Treatment of cervical Cancer module for the assessment of health related quality of life in women with cervical cancer in Addis Ababa, Ethiopia |
| title_full | Reliability and validity of the Amharic version of European Organization for Research and Treatment of cervical Cancer module for the assessment of health related quality of life in women with cervical cancer in Addis Ababa, Ethiopia |
| title_fullStr | Reliability and validity of the Amharic version of European Organization for Research and Treatment of cervical Cancer module for the assessment of health related quality of life in women with cervical cancer in Addis Ababa, Ethiopia |
| title_full_unstemmed | Reliability and validity of the Amharic version of European Organization for Research and Treatment of cervical Cancer module for the assessment of health related quality of life in women with cervical cancer in Addis Ababa, Ethiopia |
| title_short | Reliability and validity of the Amharic version of European Organization for Research and Treatment of cervical Cancer module for the assessment of health related quality of life in women with cervical cancer in Addis Ababa, Ethiopia |
| title_sort | reliability and validity of the amharic version of european organization for research and treatment of cervical cancer module for the assessment of health related quality of life in women with cervical cancer in addis ababa ethiopia |
| topic | Cervical Cancer HRQoL Validation Amharic version EORTC QLQ-CX24 |
| url | http://link.springer.com/article/10.1186/s12955-019-1089-x |
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