Virulence Factors in Coagulase-Negative Staphylococci
Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being <i>S. epidermidis</i>, <i>S. haemolyticus</i> and, more recently, <i>S. lugdunensis</i>, the most clinically relevant species. Despite being less vir...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-02-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/10/2/170 |
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| author | Angela França Vânia Gaio Nathalie Lopes Luís D. R. Melo |
| author_facet | Angela França Vânia Gaio Nathalie Lopes Luís D. R. Melo |
| author_sort | Angela França |
| collection | DOAJ |
| description | Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being <i>S. epidermidis</i>, <i>S. haemolyticus</i> and, more recently, <i>S. lugdunensis</i>, the most clinically relevant species. Despite being less virulent than the well-studied pathogen <i>S. aureus</i>, the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food. |
| first_indexed | 2024-03-09T05:43:29Z |
| format | Article |
| id | doaj.art-b9997f55ae85452dab1b0ca6cd7bbf2e |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-09T05:43:29Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-b9997f55ae85452dab1b0ca6cd7bbf2e2023-12-03T12:23:33ZengMDPI AGPathogens2076-08172021-02-0110217010.3390/pathogens10020170Virulence Factors in Coagulase-Negative StaphylococciAngela França0Vânia Gaio1Nathalie Lopes2Luís D. R. Melo3Laboratory of Research in Biofilms Rosário Oliveira, Centre of Biological Engineering, University of Minho, 4710-057 Braga, PortugalLaboratory of Research in Biofilms Rosário Oliveira, Centre of Biological Engineering, University of Minho, 4710-057 Braga, PortugalLaboratory of Research in Biofilms Rosário Oliveira, Centre of Biological Engineering, University of Minho, 4710-057 Braga, PortugalLaboratory of Research in Biofilms Rosário Oliveira, Centre of Biological Engineering, University of Minho, 4710-057 Braga, PortugalCoagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being <i>S. epidermidis</i>, <i>S. haemolyticus</i> and, more recently, <i>S. lugdunensis</i>, the most clinically relevant species. Despite being less virulent than the well-studied pathogen <i>S. aureus</i>, the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food.https://www.mdpi.com/2076-0817/10/2/170coagulase-negative staphylococcibiofilmsvirulence factors |
| spellingShingle | Angela França Vânia Gaio Nathalie Lopes Luís D. R. Melo Virulence Factors in Coagulase-Negative Staphylococci Pathogens coagulase-negative staphylococci biofilms virulence factors |
| title | Virulence Factors in Coagulase-Negative Staphylococci |
| title_full | Virulence Factors in Coagulase-Negative Staphylococci |
| title_fullStr | Virulence Factors in Coagulase-Negative Staphylococci |
| title_full_unstemmed | Virulence Factors in Coagulase-Negative Staphylococci |
| title_short | Virulence Factors in Coagulase-Negative Staphylococci |
| title_sort | virulence factors in coagulase negative staphylococci |
| topic | coagulase-negative staphylococci biofilms virulence factors |
| url | https://www.mdpi.com/2076-0817/10/2/170 |
| work_keys_str_mv | AT angelafranca virulencefactorsincoagulasenegativestaphylococci AT vaniagaio virulencefactorsincoagulasenegativestaphylococci AT nathalielopes virulencefactorsincoagulasenegativestaphylococci AT luisdrmelo virulencefactorsincoagulasenegativestaphylococci |