High KRT17 expression in tumour budding indicates immunologically ‘hot’ tumour budding and predicts good survival in patients with colorectal cancer

High KRT17 expression in tumour budding indicates immunologically ‘hot’ tumour budding and predicts good survival in patients with colorectal cancer

Abstract Objectives Emerging evidence has demonstrated that tumour budding (TB) is negatively associated with T‐lymphocyte infiltration in CRC. Despite extensive research, the molecular characteristics of immunologically ‘hot’ TB remain poorly understood. Methods We quantified the number of TB by ha...

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Bibliographic Details
Main Authors: Wenfeng Liang, Haiqing Jie, Hao Xie, Yebohao Zhou, Wenxin Li, Liang Huang, Zhenxing Liang, Huashan Liu, Xiaobin Zheng, Ziwei Zeng, Liang Kang
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Clinical & Translational Immunology
Subjects:
colorectal cancer
keratin
prognosis
T‐lymphocyte infiltration
tumour budding
Online Access:https://doi.org/10.1002/cti2.1495

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