Outer membrane vesicles derived from Bordetella pertussis are potent adjuvant that drive Th1-biased response

Outer membrane vesicles derived from Bordetella pertussis are potent adjuvant that drive Th1-biased response

For several years, we have been committed to exploring the potential of Bordetella pertussis-derived outer membrane vesicles (OMVBp) as a promising third-generation vaccine against the reemerging pertussis disease. The results of our preclinical trials not only confirm its protective capacity agains...

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Bibliographic Details
Main Authors: Bernarda Pschunder, Lucia Locati, Oriana López, Pablo Martin Aispuro, Eugenia Zurita, Matthew Stuible, Yves Durocher, Daniela Hozbor
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
Bordetella pertussis
outer-membrane vesicles
adjuvant
Th1
antibodies
alum
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1387534/full

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