Non-invasive in vivo fluorescence imaging of apoptotic retinal photoreceptors
Abstract Phosphatidylserine externalization is an early molecular signature for apoptosis. In many retinal degenerative diseases, photoreceptor neurons die by apoptosis. Here, we report utility of the phosphatidylserine-binding conjugate of Bis(zinc(II)-dipicolylamine (Zn-DPA) with Texas-red (PSVue-...
Main Authors: | Francesca Mazzoni, Claudia Müller, Jonathan DeAssis, Deborah Lew, W. Matthew Leevy, Silvia C. Finnemann |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-38363-z |
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