Non-invasive in vivo fluorescence imaging of apoptotic retinal photoreceptors

Abstract Phosphatidylserine externalization is an early molecular signature for apoptosis. In many retinal degenerative diseases, photoreceptor neurons die by apoptosis. Here, we report utility of the phosphatidylserine-binding conjugate of Bis(zinc(II)-dipicolylamine (Zn-DPA) with Texas-red (PSVue-...

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Bibliographic Details
Main Authors: Francesca Mazzoni, Claudia Müller, Jonathan DeAssis, Deborah Lew, W. Matthew Leevy, Silvia C. Finnemann
Format: Article
Language:English
Published: Nature Portfolio 2019-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-38363-z

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